N-[(2E,4E)-5-(dimethylamino)penta-2,4-dien-1-ylidene]-N-methylmethanaminium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-[(2E,4E)-5-(dimethylamino)penta-2,4-dien-1-ylidene]-N-methylmethanaminium
• 英文别名: [(2E,4E)-5-(dimethylamino)penta-2,4-dienylidene]-dimethylazanium
• 化学式: C9H17N2+
• 分子量: 153.24
• InChiKey: JKZCMAGCABHBCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  6.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• System and Methods for Optical Imaging
  申请人：Lomnes Stephen Johnson

  公开号：US20090236541A1

  公开（公告）日：2009-09-24

  The invention relates to imaging methods and systems. The systems may comprise a white light source configured to generate light in a first wavelength range, an excitation source configured to generate light at one or more wavelengths for exciting a fluorescent substance, a first detector configured to acquire reflectance image data that represents white light reflected from a subject, and a second detector configured to acquire fluorescence image data that represents fluorescence emissions from the subject. At least one of the one or more wavelengths generated by the excitation light source is within the first wavelength range of the white light source. The fluorescent substance may be, for example, a fluorescent dye that is injected into a patient before or during a surgery. The system may also include an image processing engine and a display. The image processing engine may receive the reflectance image data and the fluorescence image data and generate a merged image in which the fluorescence image data is superimposed on the reflectance image data. The display may be used by a surgeon, for example, to more effectively visualize the surgical site during surgery.
• TUMOR MARGIN IMAGING AGENTS
  申请人：Sood Anup

  公开号：US20100143258A1

  公开（公告）日：2010-06-10

  In one aspect, the present invention provides a functionalized monodisperse polylysine comprising a linear monodisperse polylysine chain comprising constituent lysine monomer residues containing appended C 4 -C 24 polyethylene glycol groups and at least one appended fluorescent dye moiety is provided.
• NOVEL LABELED CHEMICALLY REACTIVE AND BIOLOGICALLY ACTIVE COMJUGATES, AND METHODS AND COMPOSITIONS THEREOF
  申请人：Sun Yi

  公开号：US20150361090A1

  公开（公告）日：2015-12-17

  The invention generally relates to novel fluorophore-labeled, bi- or multi-functional, chemically reactive and/or biologically active conjugates, and related compositions and methods thereof.
• METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING
  申请人：Cornell University

  公开号：US20150328340A1

  公开（公告）日：2015-11-19

  The invention is directed to fluorophore-containing compositions and configurations wherein proximity between the fluorophore and one or more protective agents (PAs) modifies the lifetime of fluorescent and/or dark states, their frequency of occurrence, and the total lifetime of fluorescence in order to appropriately modify the photophysical characteristics of the fluorophore. The invention is also directed to methods that utilize these compositions and configurations.
• FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A PH-TRIGGERED POLYPEPTIDE
  申请人：Rhode Island Council on Postsecondary Education

  公开号：US20190231904A1

  公开（公告）日：2019-08-01

  The present subject matter provides compounds, compositions, and methods for identifying, monitoring, treating, and removing diseased tissue. Compounds, compositions, and methods for identifying, monitoring, and detecting circulating fluids such as blood are also provided.

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