2,2,3,3,4,4,4-heptafluoro-N-(2-hydroxyethyl)-N-methylbutanamide

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: 2,2,3,3,4,4,4-heptafluoro-N-(2-hydroxyethyl)-N-methylbutanamide
• 英文别名: 2,2,3,3,4,4,4-Heptafluoro-N-(2-hydroxyethyl)-N-methylbutanamide
• 化学式: C₇H₈F₇NO₂
• 分子量: 271.135
• InChiKey: LVLGIETZPOZQTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  2,2,3,3,4,4,4-heptafluoro-N-(2-hydroxyethyl)-N-methylbutanamide 在 dimethyl sulfide borane 作用下， 以 四氢呋喃 为溶剂， 以91 %的产率得到2-((2,2,3,3,4,4,4-heptafluorobutyl)(methyl)amino)ethan-1-ol
  参考文献：
  名称：

  FLUORINATED ZWITTERIONIC POLYMERS AND METHODS OF USE

  摘要：

  Fluorinated monomer compositions having the formula: A-L-Z (1), wherein A is a polymerizable group (e.g., a vinyl group); L is a bond or linking portion; Z is a zwitterionic moiety or a zwitterionic precursor moiety containing a protecting group capable of deprotection to form a charged group; wherein at least one hydrogen atom in A, L, and/or Z in Formula (1) is substituted by a fluorinated hydrocarbon group, wherein the fluorinated hydrocarbon group contains 1-12 carbon atoms and precisely or at least one, two, three, four, five, or six fluorine atoms. Also described herein are fluorinated zwitterionic polymers derived from such monomers. Also described herein are mixed-charge zwitterionic polymers. Other aspects include methods for producing the monomers and polymers, bulk material (e.g., hydrogel or copolymer hybrid) compositions of any of the zwitterionic polymers described herein, fouling-resistant and/or fouling releasing surfaces and objects, and nanoparticles containing the polymer or bulk material.

  公开号：

  WO2023249926A2
• 作为产物：
  描述：

  N-甲基-2-羟基乙胺 、 庚氟丁酸乙酯 以 氯仿 为溶剂， 以99 %的产率得到2,2,3,3,4,4,4-heptafluoro-N-(2-hydroxyethyl)-N-methylbutanamide
  参考文献：
  名称：

  FLUORINATED ZWITTERIONIC POLYMERS AND METHODS OF USE

  摘要：

  Fluorinated monomer compositions having the formula: A-L-Z (1), wherein A is a polymerizable group (e.g., a vinyl group); L is a bond or linking portion; Z is a zwitterionic moiety or a zwitterionic precursor moiety containing a protecting group capable of deprotection to form a charged group; wherein at least one hydrogen atom in A, L, and/or Z in Formula (1) is substituted by a fluorinated hydrocarbon group, wherein the fluorinated hydrocarbon group contains 1-12 carbon atoms and precisely or at least one, two, three, four, five, or six fluorine atoms. Also described herein are fluorinated zwitterionic polymers derived from such monomers. Also described herein are mixed-charge zwitterionic polymers. Other aspects include methods for producing the monomers and polymers, bulk material (e.g., hydrogel or copolymer hybrid) compositions of any of the zwitterionic polymers described herein, fouling-resistant and/or fouling releasing surfaces and objects, and nanoparticles containing the polymer or bulk material.

  公开号：

  WO2023249926A2