PEG-8/SMDI共聚物 | 39444-87-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: PEG-8/SMDI共聚物
• 英文名称: Ethane-1,2-diol;1-isocyanato-4-[(4-isocyanatocyclohexyl)methyl]cyclohexane
• CAS: 39444-87-6；112666-65-6
• 化学式: C17H28N2O4
• 分子量: 324.4
• InChiKey: KWXITRWAHDYEEE-UHFFFAOYSA-N

物化性质

• LogP：
  5.476 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2.14
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  99.3
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Use of vitamin D analogs to treat conditions related to increased oxidative stress
  申请人：——

  公开号：US20020042403A1

  公开（公告）日：2002-04-11

  A pharmaceutical composition for reducing the rate at which skin ages or for treating cancer, acne or rosacea. The composition comprises a pharmaceutically acceptable excipient in combination with 26,27-hexafluoro-1,25-dihydroxy vitamin D 3 . The composition is preferably administered topically at a concentration of about 0.0001% weight to about 0.01% weight.

  一种药物组合物，用于降低皮肤老化速度或治疗癌症、痤疮或酒渣鼻。该组合物由药学上可接受的赋形剂与 26,27-六氟-1,25-二羟基维生素 D 3 .该组合物最好以约 0.0001% 重量比至约 0.01% 重量比的浓度局部给药。
• TOPICAL FORMULATIONS FOR THE TREATMENT OF NAIL FUNGAL DISEASES
  申请人：Bertek Pharmaceuticals, Inc.

  公开号：EP1071413A1

  公开（公告）日：2001-01-31
• POLYURETHANES AS TOPICAL SKIN PROTECTANTS
  申请人：Bertek Pharmaceuticals, Inc.

  公开号：EP1119374B1

  公开（公告）日：2014-03-12
• EP1119374A4
  申请人：——

  公开号：EP1119374A4

  公开（公告）日：2007-08-01
• Skin Treatment Systems
  申请人：Fox Charles

  公开号：US20100080764A1

  公开（公告）日：2010-04-01

  A basic facial and body treatment cosmetic formulation is a combination of a cationic emulsifying agent, an oil soluble liquid polymer and a naturally occurring lactate buffer system. The basic formulation is a starter system that can be specialized to skin moisturizers, skin lighteners, skin pigmenting agents, sunscreens, antioxidants, line reducing products, wrinkle reducing products, anti-cellulite products, pharmaceuticals and the like.