萤光红BK | 52372-36-8

• 物质功能分类: 染料及颜料 - 染料 - 溶剂染料
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃吡啶类
• 中文名称: 萤光红BK
• 中文别名: 溶剂红196；溶剂红 196；萤光红 BK；荧光红BK
• 英文名称: 3-diethylamino-7-oxo-7H-chromeno[3',2'-3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile
• 英文别名: 3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile；7H-[1]Benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile, 3-(diethylamino)-7-oxo-；17-(diethylamino)-11-oxo-14-oxa-3,10-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-1(21),2,4,6,8,12,15(20),16,18-nonaene-12-carbonitrile
• CAS: 52372-36-8
• 化学式: C₂₃H₁₈N₄O₂
• 分子量: 382.422
• InChiKey: UTTFXJZCRVZYQF-UHFFFAOYSA-N

物化性质

• 沸点：
  575.3±60.0 °C(Predicted)
• 密度：
  1.34±0.1 g/cm3(Predicted)
• LogP：
  3.6 at 25℃
• 物理描述：
  DryPowder

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  71.2
• 氢给体数：
  0
• 氢受体数：
  5

制备方法与用途

化学性质
带荧光的红色粉末，不溶于水，并且具有优异的耐晒牢度和耐热稳定性，可达到300℃。

用途
荧光红 BK 适用于聚苯乙烯、聚氯乙烯及聚碳酸酯塑料着色，特别适合用于浅色透明材质的染色。

生产方法
该产品可以通过以下两种方法制备：

1. 以4-二乙氨基水杨醛、2-氰甲基苯并咪唑和氰乙酸甲酯为原料。首先，在DMF溶剂中将4-二乙氨基水杨醛与2-氰甲基苯并咪唑进行缩合，随后与氰乙酸甲酯反应生成目标产物；经过后处理、干燥步骤即可得到成品。
2. 以C.I.Solvent Red 197为原料：在反应瓶中加入C.I.溶剂红197 11.4克和浓盐酸200毫升，于100-103℃下回流2.5小时，并通过测量来确定反应终点。反应结束后加入冰块500克并用50%的NaOH溶液中和至pH=7.5，随后进行过滤、水洗及干燥步骤以获得所需的红色染料。

上下游信息

• 上游原料

  中文名称	英文名称	CAS号	化学式	分子量
  溶剂红197	3-diethylamino-7-imino-7H-chromeno[3',2'-3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile	52372-39-1	C23H19N5O	381.437

反应信息

• 作为产物：
  描述：

  溶剂红197 在 盐酸 、 水 作用下， 反应 3.0h， 生成 萤光红BK
  参考文献：
  名称：

  Preparation and photophysical properties of thin films of coumarin dyes

  摘要：

  The results from investigating the photophysical properties of new coumarin dyes synthesized and incorporated into Langmuir-Blodgett films are presented. A method for forming monolayers on the surface of a water/air interface is proposed. The phase states of mixed monolayers on a water surface are studied. It is found that mixed monolayers of amphiphilic polyampholyte and dye allow us to obtain more stable and condensed films, relative to films of single components. The spectral and luminescent properties of synthesized dyes in solution and in Langmuir-Blodgett films are studied.

  DOI：

  10.1134/s0036024413070133

文献信息

• [EN] NANOPIGMENTS<br/>[FR] NANOPIGMENTS
  申请人：NVA IP HOLDINGS PTY LTD

  公开号：WO2010054441A1

  公开（公告）日：2010-05-20

  The present invention relates to a dye monomer of general formula (I): A - X - R - O - C(O) - O - CH2- C(H) = CH2,wherein A is a dye molecule and both X and R are optional linkers. The present invention also relates to particles comprising a copolymer of said dye monomer and an ethylenically unsaturated monomer, to a method of producing said particles, to the use of said particles as nanopigments and to polymer dispersions comprising said particles as nanopigments.

  本发明涉及一种一般式(I)的染料单体：A - X - R - O - C(O) - O - CH2- C(H) = CH2，其中A是染料分子，X和R均为可选的连接物。本发明还涉及包含所述染料单体和乙烯基不饱和单体的共聚物的颗粒，以及制备所述颗粒的方法，以及将所述颗粒用作纳米颜料的用途，以及包含所述颗粒作为纳米颜料的聚合物分散体。
• CENTRAL NERVOUS SYSTEM TISSUE-LABELING COMPOSITION, METHOD FOR LABELING CENTRAL NERVOUS SYSTEM TISSUE, AND SCREENING METHOD USING CENTRAL NERVOUS SYSTEM TISSUE-LABELING COMPOSITION
  申请人：CANON KABUSHIKI KAISHA

  公开号：US20160361442A1

  公开（公告）日：2016-12-15

  To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).

  提供一种中枢神经系统组织标记组合物，用于标记中枢神经系统组织。此外，本发明的另一个目标是提供一种非侵入性标记中枢神经组织系统的方法。进一步，本发明的另一个目标是提供一种使用上述中枢神经系统组织标记组合物的筛选方法。中枢神经系统组织标记组合物包含至少一种由一般式（1）或（7）表示的化合物作为活性成分。
• COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS
  申请人：Oystershell NV

  公开号：EP3884933A1

  公开（公告）日：2021-09-29

  The current invention relates to a composition for the topical treatment of fungal infections in nails, comprising at least one physiologically acceptable carboxylic acid capable of reducing the pH in keratinous tissue, in particular nails, of a treated person below 4.0, preferably in the range of 1.5 - 4.0, a physiologically acceptable carrier comprising at least one C1-C4 alkyl ester of lactic acid, and at least one physiologically acceptable fluorescent whitening agent. The invention relates to the use of said composition for the preparation of a product suitable for treatment of fungal infections. The invention also relates to the use of said composition for the treatment of a fungal infection.

  本发明涉及一种用于局部治疗指甲真菌感染的组合物，该组合物包含至少一种生理上可接受的羧酸，该羧酸能够将受治疗者的角质组织（尤其是指甲）中的 pH 值降至 4.0 以下，最好在 1.5 - 4.0 之间；一种生理上可接受的载体，该载体包含至少一种乳酸的 C1-C4 烷基酯；以及至少一种生理上可接受的荧光增白剂。本发明涉及使用所述组合物制备适用于治疗真菌感染的产品。本发明还涉及使用所述组合物治疗真菌感染。
• Breach or contamination indicating article, optionally with pre-warning indicator
  申请人：Ansell Limited

  公开号：US10065210B2

  公开（公告）日：2018-09-04

  Provided, among other things, is a breach or contamination indicating elastomeric article for indicating a breach or contamination by a selected chemical or group of chemicals, the article having an exterior and interior and comprising: (1) an interior elastomeric layer selected to resist permeation by the selected chemical(s); and (2) exterior thereto, a contiguous or dis-contiguous first indicating layer comprising a dye or pigment and an opacifying agent, the dye or pigment providing the layer with color, the first indicating layer changing color and/or opacity when contacted with a selected chemical such regions of the article where the layer is so contacted contrast with non-contacted regions. A subsequent, interior layer can provide a safety buffer allowing for removal or disposal prior to any potential for harm. A second, interior indicating layer can be used to make the warning louder when a serious breach is occurring.

  除其他外，还提供了一种破损或污染指示弹性体物品，用于指示破损或所选化学品或化学品组的污染，该物品具有外部和内部，包括：(1) 内部弹性体层，该层被选定为可抵抗所选化学品的渗透；以及(2) 外部连续或不连续的第一指示层，该层包括染料或颜料：(1)内部的弹性体层，该层被选定用于抵抗所选化学品的渗透；以及(2)外部的连续或不连续的第一指示层，该层由染料或颜料以及不透明剂组成，染料或颜料为该层提供颜色，当第一指示层与所选化学品接触时，该层的颜色和/或不透明度发生变化，该层接触的区域与未接触的区域形成对比。随后的内部指示层可以提供安全缓冲，以便在可能造成危害之前进行移除或处理。第二层内部指示层可用于在发生严重破坏时发出更响亮的警告。
• MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN
  申请人：Arkema France

  公开号：EP1848763A1

  公开（公告）日：2007-10-31