The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
本公开提供了一些非自然生成的多
酚化合物,它们可以上调
载脂蛋白A-I(ApoA-I)的表达。所公开的组合物和方法可用于治疗和预防心血管疾病及相关疾病状态,包括
胆固醇或脂质相关的疾病,如动脉粥样硬化等。