hydron;1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine;dichloride

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: hydron;1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine;dichloride
• 化学式: C10H18Cl2N2
• 分子量: 237.17
• InChiKey: FBHKTSXMTASXFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.66
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  6.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] NOVEL CELL-PERMEABLE SUCCINATE COMPOUNDS<br/>[FR] NOUVEAUX COMPOSÉS DE SUCCINATE PERMÉABLES À TRAVERS LES CELLULES
  申请人：NEUROVIVE PHARMACEUTICAL AB

  公开号：WO2015155231A1

  公开（公告）日：2015-10-15

  The present invention provides novel cell-permeable succinates and cell permeable precursors of succinate aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates from mitochondrial oxidative phosphorylation, a process to which high-energy electrons are provided by the Kreb's cycle. Not all Kreb's cycle intermediates are readily permeable to the cellular membrane, one of them being succinate. The provision of the novel cell permeable succinates is envisaged to allow passage over the cellular membrane and thus the cell permeable succinates can be used to enhance mitochondrial ATP-output.

  本发明提供了新型的细胞可渗透琥珀酸盐和琥珀酸盐的细胞可渗透前体，旨在增加线粒体中的ATP产生。在真核细胞中产生和利用的大部分ATP源自线粒体氧化磷酸化，这是一个高能电子由克雷布氏循环提供的过程。并非所有克雷布氏循环中间体都能轻易渗透到细胞膜，其中之一就是琥珀酸盐。提供新型的细胞可渗透琥珀酸盐可让其通过细胞膜，因此细胞可渗透琥珀酸盐可用于增强线粒体的ATP产出。
• Method for preparing aqueous solutions containing chromogenic materials
  申请人：SAVYON DIAGNOSTICS LTD.

  公开号：EP0271713A2

  公开（公告）日：1988-06-22

  A method is described by means of which aqueous solutions containing chromogenic materials can be prepared from substantially anhydrous compositions containing all elements of the desired chromogen­containing aqueous solution, water excluded. The invention also encompasses the stable anhydrous compositions for carrying out the method, and aqueous compositions obtained thereby. The anhydrous compositions, as well as the aqueous compositions, present improved stability characteristics.

  本发明描述了一种方法，通过该方法可以从基本无水的组合物中制备出含有致色材料的水溶液，该组合物含有所需含色水溶液的所有元素，不含水。 本发明还包括用于实施该方法的稳定的无水组合物以及由此获得的水性组合物。 无水组合物以及水性组合物具有更好的稳定性。
• Device and method for breaking an ampoule
  申请人：Becton Dickinson and Company

  公开号：EP0621232A1

  公开（公告）日：1994-10-26

  The present invention is a device and method for breaking an ampoule. In particular, the device is preferably for use in an apparatus for collecting and transporting biological specimens. The device comprises a guard arrangement (10) that surrounds a frangible ampoule (40). With appropriate force applied to the guard arrangement, the frangible ampoule is ruptured.

  本发明是一种用于打破安瓿的装置和方法。特别是，该装置最好用于收集和运输生物标本的设备中。该装置包括一个环绕易碎安瓿瓶 (40) 的防护装置 (10)。当对防护装置施加适当的力时，易碎安瓿就会破裂。
• Specimen collecting and transport system
  申请人：Becton Dickinson and Company

  公开号：EP0645447A2

  公开（公告）日：1995-03-29

  A sleeve for use with a device for collecting and transporting biological specimens. The sleeve is used to exert pressure to the collection device so as to break the ampoule. The sleeve comprises means for limiting over compression of the collection device. The sleeve provides an environment to maintain the substantial viability of a specimen during transport in a collection device.

  一种与生物样本采集和运输设备配套使用的套筒。套筒用于对收集装置施加压力，从而使安瓿破裂。套筒包括限制过度压缩收集装置的装置。套筒提供了一种环境，可在收集装置中运输标本期间保持标本的实质活力。
• BOD SENSOR AND BOD MEASURING METHOD
  申请人：AKEBONO BRAKE INDUSTRY CO., LTD.

  公开号：EP0667521A1

  公开（公告）日：1995-08-16

  An electrode made of a metal or carbon, a working electrode (20) in contact with this electrode and of a microorganic germ-containing thin film, a counter electrode (7), and a reference electrode (5) as necessary are immersed in an organism-containing solution (30), and the BOD of this solution is measured by determining the quantity of an electric current flowing between the working electrode (20) and counter-electrode (7) or reference electrode (5), applying a voltage between the electrodes by a potentiostat (6). By this method, the concentrations of organic compounds can be measured directly without using an oxygen electrode even when the quantity of dissolved oxygen is small.

  将由金属或碳制成的电极、与该电极和含微生物细菌薄膜接触的工作电极 (20)、对电极 (7) 以及必要的参比电极 (5) 浸入含有机物的溶液 (30) 中，通过恒电位仪 (6) 在电极之间施加电压，确定工作电极 (20) 和对电极 (7) 或参比电极 (5) 之间的电流大小，从而测量该溶液的生化需氧量。通过这种方法，即使溶解氧的数量很少，也可以不使用氧电极直接测量有机化合物的浓度。

表征谱图