申请人:——
公开号:US20030027822A1
公开(公告)日:2003-02-06
The invention provides sodium channel modulating compounds of formula I:
1
wherein X, Y, Q, R
1
, w, and R
2
have any of the values defined in the specification, and salts thereof, which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of formula (I) or a salt thereof, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).
该发明提供了公式I的钠通道调节化合物:1其中X、Y、Q、R1、w和R2具有规范中定义的任何值,以及其盐,这些化合物对于治疗与钠通道活性相关的疾病或症状,如神经病性疼痛,具有有用性。该发明还提供了包含公式(I)的化合物或其盐的药物组合物,以及包括将这种化合物或盐用于哺乳动物(例如人类)的治疗方法。