A bone substitute material is prepared by firing and pulverizing animal bones into animal bone powder, mixing the animal bone powder and a divalent metal compound into a powdery mixture, and kneading the powdery mixture with chitosan sol. Alternatively, a bone substitute sheet is prepared by mixing at least one of apatite and animal bone powder with chitosan sol into a mixture, forming a pre-processed sheet of the mixture, and neutralizing the sheet by an aqueous solution of a compound. The bone substitute material and sheet have a pH value falling within a neutral range.
一种骨替代材料的制备方法是:将动物骨头烧制并粉碎成动物骨粉,将动物骨粉和二价
金属化合物混合成粉末状混合物,然后将粉末状混合物与
壳聚糖溶胶混合。或者,通过将
磷灰石和动物骨粉中的至少一种与
壳聚糖溶胶混合成混合物,形成混合物的预加工片材,并用化合物的
水溶液对片材进行中和,制备骨替代物片材。骨替代材料和薄片的 pH 值在中性范围内。