Cholestane-3,5,6-triol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Cholestane-3,5,6-triol
• 英文别名: (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol
• 化学式: C₂₇H₄₈O₃
• 分子量: 420.7
• InChiKey: YMMFNKXZULYSOQ-MHZASZHRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Meiosis regulating compounds
  申请人：——

  公开号：US20010003782A1

  公开（公告）日：2001-06-14

  Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.

  某些新型甾醇衍生物可以用于调节卵母细胞和雄性生殖细胞的减数分裂。
• Steroid compounds, use of these compounds for the preparation of meiosis-regulating medicaments and method for the preparation of these compounds
  申请人：Schering AG

  公开号：US20020188143A1

  公开（公告）日：2002-12-12

  The present invention relates to steroid compounds of general formula X, which may advantageously be employed to stimulate meiosis in human oocytes, the steroid being specifically characterized by amino nitrogen bonded to C 17 of the steroid skeleton via a spacer A. 1

  本发明涉及通式X的类固醇化合物，这些化合物可优势地用于刺激人卵母细胞的减数分裂，该类固醇化合物的特征在于氨基氮通过间距A.1与类固醇骨架的C17键合。
• Aminosterol compounds, their use in the preparation of meiosis-regulating medicaments and method for their preparation
  申请人：Schering Aktiengesellschaft

  公开号：EP1245572A1

  公开（公告）日：2002-10-02

  The present invention relates to steroid compounds of general formula I, which may advantageously be employed to stimulate meiosis in human oocytes, the steroid being specifically characterized by amino nitrogen bonded to C17 of the steroid skeleton via a spacer A.

  本发明涉及通式I的类固醇化合物，这些化合物可优势地用于刺激人类卵母细胞的减数分裂，该类固醇化合物的特点是通过间隔物A与类固醇骨架的C17上的氨基氮键合。
• [EN] THIOMORPHOLINO STEROID COMPOUNDS, THE USE THEREOF FOR THE PREPARATION OF MEIOSIS-REGULATING MEDICAMENTS AND METHOD FOR THE PREPARATION THEREOF<br/>[FR] COMPOSES THIOMORPHOLINO STEROIDES, LEUR UTILISATION POUR LA PREPARATION DE MEDICAMENTS REGULANT LA MEIOSE ET PROCEDE DE PREPARATION ASSOCIE
  申请人：SCHERING AG

  公开号：WO2005014613A1

  公开（公告）日：2005-02-17

  The present invention relates to thiomorpholino steroid compounds of general formula (I), which may advantageously be employed to stimulate meiosis in human oocytes, the steroid being specifically characterized by a thiomorpholino moiety bonded to C17 of the steroid skeleton via an alkylen spacer.

  本发明涉及通式(I)的硫代吗啡诺类固醇化合物，其可优选地用于刺激人卵母细胞的减数分裂，该类固醇具有通过烷基间隔连接到类固醇骨架的C17的硫代吗啡诺基团的特征。
• Thiomorpholino steroid compounds, the use thereof for the preparation of meiosis-regulating medicaments and method for the preparation thereof
  申请人：Blume Thorsten

  公开号：US20070078262A1

  公开（公告）日：2007-04-05

  The present invention relates to thiomorpholino steroid compounds of general formula I, which may advantageously be employed to stimulate meiosis in human oocytes, the steroid being specifically characterized by a thiomorpholino moiety bonded to C 17 of the steroid skeleton via an alkylen spacer.

  本发明涉及到一般式I的硫代吗啡基类固醇化合物，可以优势地用于刺激人类卵母细胞的减数分裂，该类固醇特别的特征是通过烷基间隔将硫代吗啡基与类固醇骨架的C17键合。