2,3,6-Trimethyl-thionaphthen | 91144-23-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 2,3,6-Trimethyl-thionaphthen
• 英文别名: 2,3,6-Trimethyl-benzothiophene；2,3,6-trimethyl-1-benzothiophene
• CAS: 91144-23-9
• 化学式: C₁₁H₁₂S
• 分子量: 176.282
• InChiKey: NETYMFPERAKHQJ-UHFFFAOYSA-N

物化性质

• 沸点：
  288.2±9.0 °C(Predicted)
• 密度：
  1.089±0.06 g/cm3(Predicted)
• 保留指数：
  1546.7

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  28.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• DITHIENOBENZO-THIENO[3,2-B]THIOPHENE-COPOLYMER AND ITS USE AS HIGH PERFORMANCE SOLUTION PROCESSABLE SEMICONDUCTING POLYMER
  申请人：Kastler Marcel

  公开号：US20120289672A1

  公开（公告）日：2012-11-15

  Dithienobenzo-thieno[3,2-b]thiophene-copolymers of the formula (I) wherein: pi is a monocyclic or polycyclic moiety optionally substituted with 1-4 Ra groups, wherein R a , at each occurrence, is independently hydrogen or a) a halogen, b) —(CN, c) —NO 2 , d) oxo, e) —OH, f) ═C(R b ) 2 ; g) a C 1-20 alkyl group, h) a C 2-20 alkenyl group, i) a C 2-20 alkynyl group, j) a C 1-20 alkoxy group, k) a C 1-20 alkylthio group, l) a C 1-20 haloalkyl group, m) a —Y—C 3-10 cycloalkyl group, n) a —Y—C 6-14 aryl group, o) a —Y-3-12 membered cycloheteroalkyl group, or p) a —Y-5-14 membered heteroaryl group, wherein each of the C 1-20 alkyl group, the C 2-20 alkenyl group, the C 2-20 alkynyl group, the C 3-10 cycloalkyl group, the C 6-14 aryl or haloaryl group, the 3-12 membered cycloheteroalkyl group, and the 5-14 membered heteroaryl group is optionally substituted with 1-4 R b groups; Y, at each occurrence, is independently a divalent C 1-6 alkyl group, a divalent C 1-6 haloalkyl group, or a covalent bond; and R 1 , R 2 , R 3 , at each occurrence, are independently H, a halogen, CN, a C 1-30 alkyl group, a C 2-30 alkenyl group, a C 1-30 haloalkyl group, a C 2-30 alkynyl group, a C 1-30 alkoxy group, a C(O)—C 1-20 alkyl group, a C(O)—OC 1-20 alkyl group, a Y—C 3-10 cycloalkyl group, a —Y-3-12 membered cycloheteroalkyl group, each optionally substituted with 1-5 substituents selected from a halogen, —CN, a C 1-6 alkyl group, a C 1-6 alkoxy group, and a C 1-6 haloalkyl group, -L-Ar 1 , -L-Ar 1 -—Ar 1 , -L-Ar 1 —R 4 , or -L-Ar 1 —Ar 1 —R 4 and Y, at each occurrence, is independently a divalent C 1-6 alkyl group, a divalent C 1-6 haloalkyl group, or a covalent bond; n=0, 1, 2; and o=1-1000.

  公式（I）中的Dithienobenzo-thieno [3,2-b] thiophene共聚物，其中：pi是一个单环或多环基团，可选地取代1-4个Ra基团，其中Ra在每次出现时独立地为氢或a）卤素，b）—（CN，c）—NO2，d）氧代，e）—OH，f）═C（Rb）2；g）C1-20烷基，h）C2-20烯基，i）C2-20炔基，j）C1-20烷氧基，k）C1-20烷硫基，l）C1-20卤代烷基，m）—Y—C3-10环烷基，n）—Y—C6-14芳基，o）—Y-3-12成员环杂基，或p）—Y-5-14成员杂芳基，其中每个C1-20烷基，C2-20烯基，C2-20炔基，C3-10环烷基，C6-14芳基或卤代芳基，3-12成员环杂基和5-14成员杂芳基可选地取代1-4个Rb基团；Y在每次出现时独立地为二价的C1-6烷基，二价的C1-6卤代烷基或共价键；R1，R2，R3在每次出现时独立地为H，卤素，CN，C1-30烷基，C2-30烯基，C1-30卤代烷基，C2-30炔基，C1-30烷氧基，C（O）—C1-20烷基，C（O）—OC1-20烷基，Y—C3-10环烷基，—Y-3-12成员环杂基，每个可选地取代1-5个取自卤素，—CN，C1-6烷基，C1-6烷氧基和C1-6卤代烷基的取代基，-L-Ar1，-L-Ar1-—Ar1，-L-Ar1—R4或-L-Ar1—Ar1—R4，并且Y在每次出现时独立地为二价的C1-6烷基，二价的C1-6卤代烷基或共价键；n = 0,1,2;和o = 1-1000。
• OXAZOLIDONE COMPOUND, PREPARING METHOD AND APPLICATION THEREOF
  申请人：SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES

  公开号：US20150361091A1

  公开（公告）日：2015-12-17

  The present invention relates to the field of a pharmaceutical compound, and more specifically, relates to a new oxazolidone compound, an enantiomer, a diastereoisomer and a raceme thereof, and a mixture thereof, and a pharmaceutically acceptable salt thereof, a preparation method thereof, an application thereof as a bioactive substance in a drug. The compound in the present invention has strong anticoagulant activity, does not affect the activity of thrombin, and can reduce the risk of hemorrhage. A pharmacokinetics experiment shows that the compound in the present invention further has good metabolic characteristics, and has a far better oral bioavailability than a positive contrastive agent rivaroxaban.

  本发明涉及制药化合物领域，更具体地涉及一种新的噁唑烷化合物，其对映异构体、二对映异构体和混合物，以及其药学上可接受的盐、制备方法及其在药物中作为生物活性物质的应用。本发明中的化合物具有强烈的抗凝血活性，不影响凝血酶的活性，并能降低出血风险。药代动力学实验表明，本发明中的化合物还具有良好的代谢特性，并且具有比阳性对照剂利伐沙班更好的口服生物利用度。
• DERIVES DE N-(ARYLSULFONYL)BETA-AMINOACIDES COMPORTANT UN GROUPE AMINOETHYLE SUBSTITUE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES EN CONTENANT
  申请人：Sanofi-Aventis

  公开号：EP1373233B1

  公开（公告）日：2007-09-05
• Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same
  申请人：Shibahashi Yutaka

  公开号：US20070082977A1

  公开（公告）日：2007-04-12

  An ink composition for a color-memorizing photochromic writing instrument, which comprises a photochromic agent containing a diarylethene photochromic compound dissolved, dispersed or suspended in a vehicle containing at least a solvent and a binder.
• METHOD OF LIQUID FUEL DESULFURIZATION
  申请人：ALLIANT TECHSYSTEMS, INC.

  公开号：US20140166539A1

  公开（公告）日：2014-06-19

  Disclosed herein are systems and methods for vortex tube desulfurization of jet fuels. Also disclosed are processes for separation of closely boiling species in a mixture of miscible fluids.