(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one | 124478-60-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
• CAS: 124478-60-0
• 化学式: C₂₉H₃₇NO₂
• 分子量: 431.6
• InChiKey: RTCKAOKDXNYXEH-LMOUXUHNSA-N

物化性质

• 熔点：
  >67°C (dec.)
• 溶解度：
  可溶于氯仿（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  32
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• A composition or group of compositions for the treatment of human cells
  申请人：Flamina Holding AG

  公开号：EP2868320A1

  公开（公告）日：2015-05-06

  The invention relates to a composition for the treatment of the organelles of genetically healthy cells of human beings, particularly for preventive treatment of the cells supporting control system, comprising at least one active agent having strong competitively binding hormone antagonist properties combined with at least a first and/or a second carrier medium supporting the transport of molecules of said active agent through the cell-wall into the cytosol and organelles of cells. In preferred forms of applications, groups of at least a first and a second inventive composition are provided that comprise different carrier media and that are applicable in different parts of the body for forwarding the active agent via different pathways to a determined application zone.

  本发明涉及一种用于治疗人类基因健康细胞的细胞器，特别是用于预防性治疗细胞支持控制系统的组合物，该组合物由至少一种具有强竞争性结合激素拮抗剂特性的活性剂与至少第一和/或第二种支持所述活性剂分子通过细胞壁转运至细胞的细胞质和细胞器的载体介质结合而成。在优选的应用形式中，至少提供一组第一和第二发明组合物，这些组合物包含不同的载体介质，适用于身体的不同部位，通过不同的途径将活性剂输送到确定的应用区域。