(2S)-4-cyclohexylbutan-2-amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (2S)-4-cyclohexylbutan-2-amine
• 化学式: C₁₀H₂₁N
• 分子量: 155.28
• InChiKey: PGKIYCIVGXRFTD-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• BETA-HAIRPIN PEPTIDOMIMETICS
  申请人：POLYPHOR AG

  公开号：US20200231629A1

  公开（公告）日：2020-07-23

  Bet-hairpin peptidomimetics of the general formula (I), cyclo[P 1 -P 2 -P 3 -P 4 -P 5 -P 6 -P 7 -P 8 -P 9 -P 10 -P 11 -P 12 -T 1 -T 2 ], and pharmaceutically acceptable salts thereof, with P 1 to P 12 , T 1 and T 2 being elements as defined in the description and the claims, have Gram-negative antimicrobial activity to e.g. inhibit the growth or to kill microorganisms such as Klebsiella pneumoniae and/or Acinetobacter baumannii and/or Escherichia coli. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.