4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;sulfuric acid | 77101-45-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;sulfuric acid
• CAS: 77101-45-2
• 化学式: C8H13NO7S
• 分子量: 267.26
• InChiKey: RAUYCNZDCZFBJP-QRPNPIFTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.56
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  170
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• Xamoterol for the treatment of obesity
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0227339A2

  公开（公告）日：1987-07-01

  The invention concerns the use of N-(2-[-(RS-2-hydroxy-3-(4-hydroxyphenoxy)propylamino)ethyl)-morpholinoform- amide or a salt thereof in the production of a medicament for the treatment of obesity and/or related conditions in warm-blooded animals including man.

  本发明涉及 N-(2-[-(RS-2-羟基-3-(4-羟基苯氧基)丙基氨基)乙基]-吗啉酰胺或其盐在生产治疗包括人类在内的温血动物肥胖症和/或相关疾病的药物中的用途。
• CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME
  申请人：Ecolab USA Inc.

  公开号：US20170306504A1

  公开（公告）日：2017-10-26

  Disclosed are methods for inhibiting the corrosion of metal containments such as carbon-steel pipes used in oil recovery processes, the methods comprising adding urine and/or compositions comprising urine to water sources to form corrosion inhibitor compositions, and contacting metal containments with the corrosion inhibitor compositions. The water sources are for example aqueous solutions that are corrosive to metal containments such as carbon-steel pipes. Compositions comprising urine that provide reduced corrosion or corrosion inhibition are also described. Metal containment assemblages comprising corrosion inhibitor compositions and a metal containment are also described.
• METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS)
  申请人：Oregon Institute of Science and Medicine

  公开号：US20190391092A1

  公开（公告）日：2019-12-26

  A method for constructing a metabolic profile of a mammalian (such as a human) subject from one of more urine samples from the subject uses magnetic resonance mass spectrometry (MRMS) for the rapid and inexpensive quantitative measurement of at least 4,000 urinary chemical substances in a single analysis. The method for metabolic profiling measures thousands of urinary substances in a urine sample from a mammalian subject in a single assay. Many of these substances can be of mammalian metabolic origin. The measurements of types and amounts of urinary substances can be correlated to assessments of present or future health of the subject.
• COMPOSITIONS AND METHODS FOR MODULATING METABOLIC REGULATORS OF T CELL PATHOGENICITY
  申请人：The Broad Institute, Inc.

  公开号：US20220142948A1

  公开（公告）日：2022-05-12

  The subject matter disclosed herein is generally directed to modulation of Th17 differentiation and pathogenicity by use of metabolic targets. The metabolic targets are the molecules of the polyamine pathway or glycolysis pathway. Modulation of the polyamine pathway can shift Th17 pathogenicity and shift the transcriptome of Th17 cells to a Treg or Th1 transcriptome. The polyamine analogue DFMO can be used to modulate an inflammatory response. Inhibitors of enzymes in the glycolysis pathway can shift Th17 pathogenicity.
• US4933340A
  申请人：——

  公开号：US4933340A

  公开（公告）日：1990-06-12