Ursodeoxycholic acid 3-sulfate | 68780-73-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Ursodeoxycholic acid 3-sulfate
• 英文别名: (4R)-4-[(3S,7S,8R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• CAS: 68780-73-4
• 化学式: C₂₄H₄₀O₇S
• 分子量: 472.6
• InChiKey: WHMOBEGYTDWMIG-ROKSHQGPSA-N

物化性质

• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  130
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Methods of treating injuries of the nervous system associated with hemorrhage
  申请人：Steer J Clifford

  公开号：US20060135494A1

  公开（公告）日：2006-06-22

  Methods for treating injuries of the nervous system associated with hermorrhage by administering a hydrophilic bile acid, such as ursodeoxycholic acid (UDCA), salts thereof, and analogs thereof (e.g., glyco-, tauro-ursodeoxycholic acid, and other conjugated derivative).

  通过施用亲水性胆汁酸，如熊去氧胆酸（UDCA）、其盐类及其类似物（如甘油、牛磺酸熊去氧胆酸及其他共轭衍生物）来治疗与大出血有关的神经系统损伤的方法。
• Sodium salt of ursodeoxycholic sulphate
  申请人：ISTITUTO BIOLOGICO CHEMIOTERAPICO "ABC" S.p.A.

  公开号：EP0117570B1

  公开（公告）日：1986-09-03
• SULFATE CONJUGATES OF URSODEOXYCHOLIC ACID, AND THEIR BENEFICIAL USE IN INFLAMMATORY DISORDERS AND OTHER APPLICATIONS
  申请人：CHILDREN'S HOSPITAL MEDICAL CENTER

  公开号：EP0871452A2

  公开（公告）日：1998-10-21
• METHODS OF TREATING INJURIES OF THE NERVOUS SYSTEM ASSOCIATED WITH HEMORRHAGE
  申请人：REGENTS OF THE UNIVERSITY OF MINNESOTA

  公开号：EP1575578A2

  公开（公告）日：2005-09-21
• EP1575578A4
  申请人：——

  公开号：EP1575578A4

  公开（公告）日：2007-10-10