申请人:Biosignal Australia Pty Limited
公开号:EP1787988A2
公开(公告)日:2007-05-23
The present invention relates to the side chain functionalisation of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, carboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.
本发明涉及芬普罗内酯(卤代 3-烷基-5-亚甲基-2(5H)-呋喃酮)及其合成类似物的侧链官能化,从而得到在烷基链中被卤素、氧或氮官能团取代的芬普罗内酯,特别是芬普罗内酯醇、羧酸酯、硫酸酯和磺酸酯、醚、醛、酮、酸、酰胺、硝基衍生物、疏水性、亲水性和亲氟烷基衍生物及聚合物。