7-Isoquinolinesulfonyl chloride, 3-chloro- | 478647-02-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 7-Isoquinolinesulfonyl chloride, 3-chloro-
• 英文别名: 3-chloroisoquinoline-7-sulfonyl chloride
• CAS: 478647-02-8
• 化学式: C₉H₅Cl₂NO₂S
• 分子量: 262.11
• InChiKey: IOBCIDHYESEXKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA<br/>[FR] DERIVES PYRROLIDINE-2-UN COMME INHIBITEURS DE FACTEUR XA
  申请人：GLAXO GROUP LTD

  公开号：WO2002100886A1

  公开（公告）日：2002-12-19

  The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.

  本发明涉及式(Ic)化合物、其制备过程、含有它们的药物组合物以及它们在医学上的应用，特别是在改善适用于因子Xa抑制剂的临床状况方面的应用。
• Chemical compounds
  申请人：Chan Chuen

  公开号：US20060160886A1

  公开（公告）日：2006-07-20

  The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.

  本发明涉及式(Ic)化合物，其制备方法，含有它们的药物组合物以及它们在医学上的应用，特别是在改善适应于Xa因子抑制剂的临床状况方面的应用。
• Pyrrolidin-2-one derivatives as inhibitors of factor xa
  申请人：——

  公开号：US20040152697A1

  公开（公告）日：2004-08-05

  The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated. 1

  本发明涉及公式（Ic）化合物，它们的制备过程，含有它们的药物组合物，以及它们在医学上的应用，特别是在改善适合使用因子Xa抑制剂的临床症状方面的应用。
• Chemicals compounds
  申请人：GLAXO GROUP LIMITED

  公开号：EP1839659A2

  公开（公告）日：2007-10-03

  The invention relates to compounds of formula (Ic) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.

  本发明涉及式 (Ic) 的化合物 的制备工艺、含有它们的药物组合物以及它们在医学中的用途，特别是在改善Xa因子抑制剂适用的临床症状中的用途。
• PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA
  申请人：GLAXO GROUP LIMITED

  公开号：EP1395606B1

  公开（公告）日：2007-05-02