C-bicyclohexyl-1-yl-methylamine | 4352-48-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: C-bicyclohexyl-1-yl-methylamine
• 英文别名: [1,1'-Bi(cyclohexan)]-1-ylmethanamine；(1-cyclohexylcyclohexyl)methanamine
• CAS: 4352-48-1
• 化学式: C₁₃H₂₅N
• mdl: MFCD20547603
• 分子量: 195.348
• InChiKey: FYNYEZQHKOXSEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  bicyclohexyl-1-carboxamide 在 lithium aluminium tetrahydride 作用下， 生成 C-bicyclohexyl-1-yl-methylamine
  参考文献：
  名称：

  Charpentier-Morize, Bulletin de la Societe Chimique de France, 1954, p. 497,501

  摘要：

  DOI：

文献信息

• 1-Methyl-1h-imidazole-5-carboxylic acid derivatives
  申请人：JANSSEN PHARMACEUTICA N.V.

  公开号：EP0273531A1

  公开（公告）日：1988-07-06

  Novel 1-methyl-1H-imidazole-5-carboxylic acid derivatives of formula R1 is hydrogen or mercapto; R2 is hydrogen, C1-C7alkyl, C3-C7alkenyl, C3-C7alkynyl, C3-C7cycloalkyl, C5-C7cycloalkenyl; said C1-C7alkyl, C3-C7alkenyl, C3-C7alkynyl, C3-C7cycloalkyl, C5-C7cycloalkenyl being optionally substituted; R3 is C4-C13alkyl, C3-C7cycloalkyl, or C5-C7cycloalkenyl each unsubstituted or substituted; L is cyano, -COOR4, or a group -C( = G)-D-R6; a salt or stereoisomeric form thereof, which compounds are herbicidals; compositions containing such compounds as active ingredient and methods of preparing said compounds and compositions.

  式中的新型 1-甲基-1H-咪唑-5-羧酸衍生物 R1 是氢或巯基； R2 是氢、C1-C7烷基、C3-C7烯基、C3-C7炔基、C3-C7环烷基、C5-C7环烯基；所述C1-C7烷基、C3-C7烯基、C3-C7炔基、C3-C7环烷基、C5-C7环烯基被任选取代； R3 是各自未被取代或取代的 C4-C13 烷基、C3-C7 环烷基或 C5-C7 环烯基； L 是氰基、-COOR4、 或基团-C( = G)-D-R6； 其盐或立体异构体形式，这些化合物为除草剂；含有此类化合物作为活性成分的组合物以及制备所述化合物和组合物的方法。
• 6-SUBSTITUTED NICOTINAMIDE DERIVATIVES AS OPIOID RECEPTOR ANTAGONISTS
  申请人：ELI LILLY AND COMPANY

  公开号：EP1613597B1

  公开（公告）日：2007-11-07
• Gastrin releasing peptide compounds
  申请人：Cappelletti Enrico

  公开号：US20060239923A1

  公开（公告）日：2006-10-26

  New and improved compounds for use in diagnostic imaging or therapy having the formula M-N—O—P-G, wherein M is an optical label or a metal chelator (in the form complexed with a metal radionuclide or not), N—O—P is the linker, and G is the GRP receptor targeting peptide. Methods for imaging a patient and/or providing radiotherapy or phototherapy to a patient using the compounds of the invention are also provided. Methods and kits for preparing a diagnostic imaging agent from the compound is further provided. Methods and kits for preparing a radiotherapeutic agent is further provided.
• US4832732A
  申请人：——

  公开号：US4832732A

  公开（公告）日：1989-05-23
• US8444954B2
  申请人：——

  公开号：US8444954B2

  公开（公告）日：2013-05-21