4,7-Dimethyl-2-methylidene-1,3-dioxepane | 80649-13-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧环庚烷
• 英文名称: 4,7-Dimethyl-2-methylidene-1,3-dioxepane
• CAS: 80649-13-4
• 化学式: C₈H₁₄O₂
• 分子量: 142.2
• InChiKey: YRIZQBRESDQTOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] BIODEGRADABLE TREHALOSE GLYCOPOLYMERS<br/>[FR] GLYCOPOLYMÈRES BIODÉGRADABLES DE TRÉHALOSE
  申请人：UNIV CALIFORNIA

  公开号：WO2016025668A1

  公开（公告）日：2016-02-18

  Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general structure R5-[R1R2C - CR3R4]n-[DG]m-R6, wherein R1-R4 are independently selected from hydrogen or a side chain comprising at least one carbon atom, and wherein at least one of R1-R4 is a side chain comprising -L-trehalose, wherein L is a linker molecule that links trehalose to the monomer through at least one of the trehalose hydroxyl groups (-OH), wherein DG is a biodegradable group, and wherein R5 and R6 are end groups.

  生物可降解海藻糖共聚物的结构和制备方法被披露。具体来说，生物可降解海藻糖共聚物由一般结构R5-[R1R2C - CR3R4]n-[DG]m-R6组成，其中R1-R4独立地选自氢或包含至少一个碳原子的侧链，且R1-R4中至少有一个是包含-L-海藻糖的侧链，其中L是将海藻糖通过至少一个海藻糖羟基（-OH）连接到单体的连接分子，DG是一个生物可降解基团，R5和R6是末端基团。
• Degradable polymers
  申请人：Matyjaszewski Krzysztof

  公开号：US20070155926A1

  公开（公告）日：2007-07-05

  Polymers comprising a polymer backbone comprising one or more degradable units are described. The polymer may additionally comprise two or more polymer segments comprising radically (co)polymerizable vinyl monomer units. The degradable units may be independently selected from, but not limited to, at least one of hydrodegradable, photodegradable and biodegradable units between the polymer segments and dispersed along the polymer backbone. The degradable units may be derived from one or more monomers comprising a heterocyclic ring that is capable of undergoing radical ring opening polymerization, a coupling agent, or from a polymerization initiator, radically polymerizable monomers, as well as other reactive sources. Embodiments of the degradable polymer of claim are capable of degrading by at least one of a hydrodegradation, photodegradation or biodegradation mechanisms to form at least one of telechelic oligomer and telechelic polymeric fragments of the polymer. The degradable polymer may be able to degrade into polymer fragments having a molecular weight distribution of less than 5, or in certain applications it may be preferable for embodiments of the polymer to be capable of forming polymer fragments having a molecular weight distribution of the polymer fragments less than 3.0 or even less than 2.5. Embodiments of the present invention also include methods of producing degradable polymers.

  本发明涉及一种聚合物，其聚合骨架包含一个或多个可降解单元。该聚合物可能还包括两个或更多聚合物片段，其中包括自由基（共）聚合性乙烯单体单元。可降解单元可以独立选择，但不限于，在聚合物片段之间和沿聚合物骨架分散的至少一种水解降解、光降解和生物降解单元。可降解单元可以来源于一个或多个单体，包括能够经历自由基开环聚合的杂环环、偶联剂或聚合引发剂、自由基聚合性单体以及其他反应源。该可降解聚合物的实施例能够通过至少一种水解降解、光降解或生物降解机制降解，形成聚合物的末端寡聚物和末端聚合物片段。该可降解聚合物可以降解成分子量分布小于5的聚合物片段，或在某些应用中，最好是实施例能够形成分子量分布小于3.0甚至小于2.5的聚合物片段。本发明的实施例还包括制备可降解聚合物的方法。
• Bicycloaliphatische 2-Methylen-1,3-dioxepane
  申请人：IVOCLAR AG

  公开号：EP0709387A1

  公开（公告）日：1996-05-01

  Die vorliegende Erfindung betrifft neuartige bicycloaliphatische 2-Methylen-1,3-dioxepane, die sich als Ausgangsstoffe zur Herstellung von Polymeren bzw. Copolymeren, vorzugsweise von Komposit- bzw. von Dentalmaterialien eignen. Die erfindungsgemäßen 2-Methylen-1,3-dioxepane, die sich unter Ringöffnung mit nur sehr geringem Volumenschrumpf radikalisch polymerisieren lassen, können auf einfache Weise hergestellt werden, lassen sich leicht reinigen und chemisch modifizieren und zeichnen sich durch Geruchlosigkeit und vorteilhafte physikalische Eigenschaften aus.

  本发明涉及新型双环脂族 2-亚甲基-1,3-二氧杂环庚烷，它适合作为生产聚合物或共聚物的起始材料，最好是生产复合材料或牙科材料。根据本发明的 2-亚甲基-1,3-二氧杂环庚烷可以进行辐射聚合，在开环的情况下体积收缩率非常低，生产方式简单，易于清洁和化学改性，并具有无味和有利的物理性质。
• COPOLYMER, AND MOLDED ARTICLE
  申请人：Kuraray Co., Ltd.

  公开号：EP3095800A1

  公开（公告）日：2016-11-23

  Provided are a break-resistant copolymer having high transparency and heat resistance and also having a high tensile strain at break, and a molded article. A copolymer contains 80% by mass to 98% by mass of structural units derived from a methacrylic ester monomer and 2% to 10% by mass of ester structural units derived from a cyclic ketene acetal monomer. The copolymer has a weight average molecular weight of 80, 000 or more and a molecular weight distribution of 1. 75 to 3.80.

  本发明提供了一种具有高透明度和耐热性，同时具有高断裂拉伸应变的抗断裂共聚物，以及一种模塑制品。 一种共聚物含有 80%-98%（质量百分比）由甲基丙烯酸酯单体衍生的结构单元和 2%-10%（质量百分比）由环烯酮缩醛单体衍生的酯结构单元。共聚物的平均分子量为 80,000 或以上，分子量分布为 1.75 至 3.80。
• SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION
  申请人：The Regents of the University of California

  公开号：EP3342796A1

  公开（公告）日：2018-07-04

  Structures and methods of making biodegradable trehalose co-polymers are disclosed. Specifically, biodegradable trehalose co-polymers consist of the general structure R5-[R1R2C - CR3R4]n-[DG]m-R6, wherein R1-R4 are independently selected from hydrogen or a side chain comprising at least one carbon atom, and wherein at least one of R1-R4 is a side chain comprising -L-trehalose, wherein L is a linker molecule that links trehalose to the monomer through at least one of the trehalose hydroxyl groups (-OH), wherein DG is a biodegradable group, and wherein R5 and R6 are end groups.

  本发明公开了可生物降解的三卤糖共聚物的结构和制造方法。具体来说，可生物降解的三卤糖共聚物由一般结构 R5-[R1R2C-CR3R4]n-[DG]m-R6组成，其中 R1-R4 独立地选自氢或包含至少一个碳原子的侧链、其中 R1-R4 中至少有一个是由-L-曲哈糖组成的侧链，其中 L 是连接分子，通过至少一个曲哈糖羟基（-OH）将曲哈糖与单体连接，其中 DG 是可生物降解基团，其中 R5 和 R6 是端基。