N-methyl-1-[5-(thiophen-2-yl)-1,2-oxazol-3-yl]methanamine | 852431-01-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-methyl-1-[5-(thiophen-2-yl)-1,2-oxazol-3-yl]methanamine
• 英文别名: N-methyl-1-(5-thiophen-2-yl-1,2-oxazol-3-yl)methanamine
• CAS: 852431-01-7
• 化学式: C₉H₁₀N₂OS
• mdl: MFCD08701282
• 分子量: 194.26
• InChiKey: BRMLIYZEXOZYGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.222
• 拓扑面积：
  66.3
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COMPOUNDS THAT INCREASE TELOMERASE REVERSE TRANSCRIPTASE (TERT) EXPRESSION AND METHODS FOR USING THE SAME
  申请人：Andrews William H.

  公开号：US20090143451A1

  公开（公告）日：2009-06-04

  Compounds, and methods of using the same, are provided which increase the expression of telomerase reverse transcriptase (TERT) in a cell. These compounds and methods find use in a variety of applications in which increased expression of telomerase is desired, including immortalization of cell lines and treating conditions in a subject characterized by cellular senescence.