N~1~-(2-Aminoethyl)-N~2~-phenylethane-1,2-diamine | 20541-91-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N~1~-(2-Aminoethyl)-N~2~-phenylethane-1,2-diamine
• 英文别名: N'-(2-anilinoethyl)ethane-1,2-diamine
• CAS: 20541-91-7
• 化学式: C₁₀H₁₇N₃
• mdl: MFCD00053442
• 分子量: 179.26
• InChiKey: SYFOVVQNROUCCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  50.1
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS
  申请人：Dellinger Douglas J.

  公开号：US20100076183A1

  公开（公告）日：2010-03-25

  A nucleoside monomer that is protected by a thionocarbamate protecting group is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.

  提供了一种由硫代氨基甲酸酯保护基保护的核苷单体，以及使用该核苷单体制备多核苷酸的方法。还提供了一种利用二胺去保护受保护多核苷酸的多核苷酸合成方法。
• Ink-jet ink
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0699723A2

  公开（公告）日：1996-03-06

  Disclosed herein is an ink-jet ink comprising in combination at least one compound selected from nitrogen compounds consisting of secondary amines and derivatives thereof, tertiary amines and derivative thereof, and complexes thereof and having at least one group selected from the group consisting of alkyl groups, a carboxyl group and the salts thereof, and a sulfonic group and the salts thereof, and a cyclic phosphate in a liquid medium in which a dye is dissolved or dispersed.

  本文公开了一种喷墨墨水，该墨水包含至少一种选自由仲胺及其衍生物、叔胺及其衍生物和它们的络合物组成的氮化合物，并具有至少一个选自烷基、羧基及其盐类、磺酸基及其盐类组成的基团的化合物，以及在溶解或分散染料的液体介质中的环状磷酸酯。
• Protected monomer and method of final deprotection for RNA synthesis
  申请人：Agilent Technologies, Inc.

  公开号：US10597421B2

  公开（公告）日：2020-03-24

  A method of deprotecting a solid support bound polynucleotide comprising at least one 2′-protected ribonucleotide in which a step of contacting the polynucleotide with a composition comprising a diamine is performed under conditions sufficient to deprotect and cleave the polynucleotide which remains retained on the solid support.

  一种对包含至少一种 2′-保护的核糖核苷酸的固体支持物结合的多核苷酸进行脱保护的方法，其中将多核苷酸与包含二胺的组合物接触的步骤是在足以对保留在固体支持物上的多核苷酸进行脱保护和裂解的条件下进行的。
• PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS
  申请人：Agilent Technologies, Inc.

  公开号：EP2331558A2

  公开（公告）日：2011-06-15
• Protected Monomer and Method of Final Deprotection for RNA Synthesis
  申请人：Agilent Technologies, Inc.

  公开号：US20160002282A1

  公开（公告）日：2016-01-07

  A method of deprotecting a solid support bound polynucleotide includes the step of contacting the polynucleotide with a composition comprising a diamine under conditions sufficient to deprotect the 2′-protected ribonucleotide residue. The solid support bound polynucleotide has at least one 2′-protected ribonucleotide residue, which has the following structure: wherein B P is a protected or unprotected heterocycle; R 12 is a protecting group selected from a hydrocarbyl, a substituted hydrocarbyl, an aryl, and a substituted aryl; X is O or S; and PG is a thionocarbamate protecting group.