![1-[(3R,5S,10S,13S,14S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone化学式](data:image/svg+xml;base64,<?xml version="1.0" encoding="UTF-8"?>
<svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="300" height="300" viewBox="0 0 300 300">
<defs>
<g>
<g id="glyph-0-0">
<path d="M 0.75 2.671875 L 0.75 -10.65625 L 8.3125 -10.65625 L 8.3125 2.671875 Z M 1.59375 1.828125 L 7.46875 1.828125 L 7.46875 -9.8125 L 1.59375 -9.8125 Z M 1.59375 1.828125 "/>
</g>
<g id="glyph-0-1">
<path d="M 9.734375 -10.171875 L 9.734375 -8.59375 C 9.234375 -9.0625 8.695312 -9.410156 8.125 -9.640625 C 7.5625 -9.867188 6.957031 -9.984375 6.3125 -9.984375 C 5.050781 -9.984375 4.085938 -9.597656 3.421875 -8.828125 C 2.753906 -8.066406 2.421875 -6.957031 2.421875 -5.5 C 2.421875 -4.039062 2.753906 -2.925781 3.421875 -2.15625 C 4.085938 -1.394531 5.050781 -1.015625 6.3125 -1.015625 C 6.957031 -1.015625 7.5625 -1.128906 8.125 -1.359375 C 8.695312 -1.585938 9.234375 -1.9375 9.734375 -2.40625 L 9.734375 -0.84375 C 9.210938 -0.488281 8.660156 -0.222656 8.078125 -0.046875 C 7.492188 0.128906 6.878906 0.21875 6.234375 0.21875 C 4.554688 0.21875 3.238281 -0.289062 2.28125 -1.3125 C 1.320312 -2.332031 0.84375 -3.726562 0.84375 -5.5 C 0.84375 -7.269531 1.320312 -8.664062 2.28125 -9.6875 C 3.238281 -10.707031 4.554688 -11.21875 6.234375 -11.21875 C 6.890625 -11.21875 7.507812 -11.128906 8.09375 -10.953125 C 8.675781 -10.773438 9.222656 -10.515625 9.734375 -10.171875 Z M 9.734375 -10.171875 "/>
</g>
<g id="glyph-0-2">
<path d="M 1.484375 -11.015625 L 2.96875 -11.015625 L 2.96875 -6.5 L 8.390625 -6.5 L 8.390625 -11.015625 L 9.875 -11.015625 L 9.875 0 L 8.390625 0 L 8.390625 -5.25 L 2.96875 -5.25 L 2.96875 0 L 1.484375 0 Z M 1.484375 -11.015625 "/>
</g>
<g id="glyph-0-3">
<path d="M 5.953125 -10 C 4.867188 -10 4.007812 -9.59375 3.375 -8.78125 C 2.738281 -7.976562 2.421875 -6.882812 2.421875 -5.5 C 2.421875 -4.113281 2.738281 -3.015625 3.375 -2.203125 C 4.007812 -1.398438 4.867188 -1 5.953125 -1 C 7.035156 -1 7.890625 -1.398438 8.515625 -2.203125 C 9.148438 -3.015625 9.46875 -4.113281 9.46875 -5.5 C 9.46875 -6.882812 9.148438 -7.976562 8.515625 -8.78125 C 7.890625 -9.59375 7.035156 -10 5.953125 -10 Z M 5.953125 -11.21875 C 7.492188 -11.21875 8.726562 -10.695312 9.65625 -9.65625 C 10.582031 -8.625 11.046875 -7.238281 11.046875 -5.5 C 11.046875 -3.757812 10.582031 -2.367188 9.65625 -1.328125 C 8.726562 -0.296875 7.492188 0.21875 5.953125 0.21875 C 4.398438 0.21875 3.160156 -0.296875 2.234375 -1.328125 C 1.304688 -2.367188 0.84375 -3.757812 0.84375 -5.5 C 0.84375 -7.238281 1.304688 -8.625 2.234375 -9.65625 C 3.160156 -10.695312 4.398438 -11.21875 5.953125 -11.21875 Z M 5.953125 -11.21875 "/>
</g>
<g id="glyph-1-0">
<path d="M 0.5 1.78125 L 0.5 -7.09375 L 5.53125 -7.09375 L 5.53125 1.78125 Z M 1.0625 1.21875 L 4.96875 1.21875 L 4.96875 -6.53125 L 1.0625 -6.53125 Z M 1.0625 1.21875 "/>
</g>
<g id="glyph-1-1">
<path d="M 4.078125 -3.953125 C 4.554688 -3.847656 4.925781 -3.632812 5.1875 -3.3125 C 5.457031 -3 5.59375 -2.601562 5.59375 -2.125 C 5.59375 -1.40625 5.34375 -0.847656 4.84375 -0.453125 C 4.351562 -0.0546875 3.648438 0.140625 2.734375 0.140625 C 2.421875 0.140625 2.097656 0.109375 1.765625 0.046875 C 1.441406 -0.015625 1.109375 -0.101562 0.765625 -0.21875 L 0.765625 -1.171875 C 1.035156 -1.015625 1.332031 -0.894531 1.65625 -0.8125 C 1.988281 -0.726562 2.335938 -0.6875 2.703125 -0.6875 C 3.316406 -0.6875 3.785156 -0.8125 4.109375 -1.0625 C 4.441406 -1.3125 4.609375 -1.664062 4.609375 -2.125 C 4.609375 -2.5625 4.457031 -2.898438 4.15625 -3.140625 C 3.851562 -3.390625 3.429688 -3.515625 2.890625 -3.515625 L 2.03125 -3.515625 L 2.03125 -4.328125 L 2.921875 -4.328125 C 3.410156 -4.328125 3.785156 -4.421875 4.046875 -4.609375 C 4.304688 -4.804688 4.4375 -5.09375 4.4375 -5.46875 C 4.4375 -5.84375 4.300781 -6.128906 4.03125 -6.328125 C 3.769531 -6.535156 3.390625 -6.640625 2.890625 -6.640625 C 2.617188 -6.640625 2.328125 -6.609375 2.015625 -6.546875 C 1.703125 -6.484375 1.359375 -6.390625 0.984375 -6.265625 L 0.984375 -7.15625 C 1.359375 -7.257812 1.710938 -7.335938 2.046875 -7.390625 C 2.378906 -7.441406 2.691406 -7.46875 2.984375 -7.46875 C 3.734375 -7.46875 4.328125 -7.296875 4.765625 -6.953125 C 5.203125 -6.609375 5.421875 -6.144531 5.421875 -5.5625 C 5.421875 -5.15625 5.304688 -4.8125 5.078125 -4.53125 C 4.847656 -4.257812 4.515625 -4.066406 4.078125 -3.953125 Z M 4.078125 -3.953125 "/>
</g>
</g>
</defs>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 4.408356 7.153806 L 4.258036 6.446897 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 4.280072 6.550456 L 4.814211 6.069493 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 4.168548 6.426517 L 4.702686 5.945658 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 4.269209 6.459312 L 3.309043 6.147188 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 3.309043 6.147188 L 2.490195 6.742158 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 2.509852 6.742158 L 1.681177 6.140153 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill-rule="nonzero" fill="rgb(0%, 0%, 0%)" fill-opacity="1" d="M 135.289062 205.351562 L 121.085938 240.917969 L 124.078125 241.890625 L 126.96875 243.453125 L 136.484375 205.742188 "/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 1.990404 5.196229 L 3.000022 5.196229 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 3.000022 5.196229 L 3.50478 4.321826 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 3.50478 4.338483 L 2.99516 3.455804 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 3.009644 3.464184 L 2.000025 3.464184 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 2.000025 3.464184 L 1.500027 4.330103 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 1.500027 4.330103 L 0.490408 4.330103 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 0.504789 4.338483 L -0.00483109 3.455804 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill-rule="nonzero" fill="rgb(0%, 0%, 0%)" fill-opacity="1" d="M 78.703125 107.132812 L 57.464844 138.886719 L 60.1875 140.460938 L 62.277344 143.453125 L 79.792969 107.761719 "/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 0.490408 2.598058 L 1.500027 2.598058 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 1.500027 2.598058 L 2.004784 1.723758 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 2.004784 1.740415 L 1.495164 0.857736 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 1.509648 0.866116 L 0.490408 0.866116 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 0.504789 0.857736 L -0.00483109 1.740415 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 0.486477 0.79587 L 0.446026 0.819251 M 0.458441 0.734004 L 0.406403 0.764006 M 0.430405 0.672137 L 0.366883 0.708864 M 0.402368 0.610375 L 0.327363 0.653619 M 0.374435 0.548509 L 0.28774 0.598477 M 0.346399 0.486642 L 0.24822 0.543336 M 0.318363 0.424776 L 0.2087 0.488091 M 0.290326 0.36291 L 0.169077 0.432949 M 0.262393 0.301044 L 0.129557 0.377704 M 0.234357 0.239178 L 0.0900372 0.322563 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill-rule="nonzero" fill="rgb(0%, 0%, 0%)" fill-opacity="1" d="M 117.007812 108.074219 L 146.171875 110.59375 L 146.171875 104.300781 L 117.007812 106.816406 "/>
<path fill-rule="nonzero" fill="rgb(0%, 0%, 0%)" fill-opacity="1" d="M 173.578125 206.171875 L 201.828125 211.671875 L 202.484375 205.414062 L 173.710938 204.921875 "/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 3.000022 5.196229 L 3.309043 6.147188 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 1.500027 4.330103 L 2.004784 5.204505 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M 1.500027 2.598058 L 2.000025 3.464184 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<path fill="none" stroke-width="0.0333333" stroke-linecap="butt" stroke-linejoin="miter" stroke="rgb(0%, 0%, 0%)" stroke-opacity="1" stroke-miterlimit="10" d="M -0.00483109 1.723758 L 0.504789 2.606437 " transform="matrix(37.757927, 0, 0, 37.757927, 60.369912, 9.348047)"/>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-0-1" x="223.785156" y="295.550781"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-0-2" x="233.289062" y="295.351562"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-1-1" x="243.65625" y="296.222656"/>
</g>
<g fill="rgb(100%, 5.1%, 5.1%)" fill-opacity="1">
<use xlink:href="#glyph-0-3" x="243.339844" y="233.355469"/>
</g>
<g fill="rgb(100%, 5.1%, 5.1%)" fill-opacity="1">
<use xlink:href="#glyph-0-3" x="54.425781" y="14.84375"/>
</g>
<g fill="rgb(100%, 5.1%, 5.1%)" fill-opacity="1">
<use xlink:href="#glyph-0-2" x="44.140625" y="14.644531"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-0-1" x="149.476562" y="112.941406"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-0-2" x="158.980469" y="112.742187"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-1-1" x="169.347656" y="113.613281"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-0-1" x="205.910156" y="214.988281"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-0-2" x="215.410156" y="214.789062"/>
</g>
<g fill="rgb(0%, 0%, 0%)" fill-opacity="1">
<use xlink:href="#glyph-1-1" x="225.78125" y="215.65625"/>
</g>
</svg>
)
毒理性
◉ 母乳喂养期间使用总结：由于brexanolone在乳汁中含量较低且口服生物利用度低，预计brexanolone不会对哺乳婴儿造成任何不良反应。如果母亲需要使用brexanolone，这并不是停止哺乳的理由。由于在brexanolone输注过程中可能会出现过度镇静或突然失去意识的情况，建议患者在输注过程中为任何在场的儿童提供单独的护理者。
◉ 对哺乳婴儿的影响：截至修订日期，没有找到相关的已发布信息。
◉ 对泌乳和乳汁的影响：在一项针对12名健康女性进行的60小时brexanolone输注研究中，根据制造商的报告，没有影响乳汁产量的报道。
◉ Summary of Use during Lactation:Because of the low amounts of brexanolone in milk and low oral bioavailability, brexanolone would not be expected to cause any adverse effects in breastfed infants. If brexanolone is required by the mother, it is not a reason to discontinue breastfeeding. Because excessive sedation or sudden loss of consciousness can occur during brexanolone infusion, it is suggested that patients provide a separate caregiver for any child who is present during the infusion.
◉ Effects in Breastfed Infants:Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk:In a study of 12 healthy women given a 60-hour infusion of brexanolone, there were no reports of effects on milk production according to the manufacturer.
来源:Drugs and Lactation Database (LactMed)
