1,2-bis-(4-hydroxy-phenyl)-2-methyl-propane | 1187361-06-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,2-bis-(4-hydroxy-phenyl)-2-methyl-propane
• 英文别名: 4,4'-(2-methylpropane-1,2-diyl)diphenol；4-[2-(4-hydroxyphenyl)-2-methylpropyl]phenol
• CAS: 1187361-06-3
• 化学式: C₁₆H₁₈O₂
• 分子量: 242.318
• InChiKey: SOKFWRPORPTXSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,2-bis(4-methoxyphenyl)-2-methylpropane 在 三溴化硼 、 水 作用下， 以 二氯甲烷 为溶剂， 以79%的产率得到1,2-bis-(4-hydroxy-phenyl)-2-methyl-propane
  参考文献：
  名称：

  具有非极性连接原子取代基的联苄基和芪核化合物作为雌激素受体β的选择性配体

  摘要：

  一系列结构简单的联苄二醇和芪二醇核心分子，众所周知的己雌酚和己烯雌酚非甾体雌激素的结构类似物，被制备并评估为雌激素受体 (ER) 亚型选择性配体。对它们的 ERα 和 ERβ 结合的分析表明，某些取代模式产生了对 ERβ 具有 >100 倍选择性的结合亲和力。当在基于细胞的基因转录测定中进一步研究时，一些分子显示出类似的高相对转录效力选择性，有利于 ERβ。有趣的是，最具 ERβ 选择性的分子是那些在内部碳原子之一上带有非极性取代基的分子。这些化合物应该是确定 ERβ 生理作用的有用探针，

  DOI：

  10.1016/j.ejmech.2009.02.006

文献信息

• [EN] ESTROGEN RECEPTOR LIGANDS<br/>[FR] LIGANDS DU RÉCEPTEUR DES OETROGÈNES
  申请人：RADIUS HEALTH INC

  公开号：WO2010030787A1

  公开（公告）日：2010-03-18

  The invention described herein discloses bisphenol alkane compounds of formulae III and Vl and similar compounds as well as 4-[4-hydroxybenzylthio]- phenol compounds which are estrogen receptor ligands, composition containing these compounds and methods for treating various conditions using the compounds and compositions of this invention.

  本发明公开了式III和Vl的双酚烷化合物以及类似化合物，以及作为雌激素受体配体的4-[4-羟基苯甲硫基]-酚化合物，包含这些化合物的组合物，以及使用这些化合物和本发明的组合物治疗各种疾病的方法。
• Power transmission belt and process for production of the same
  申请人：Bando Chemical Industries, Ltd.

  公开号：US20030087715A1

  公开（公告）日：2003-05-08

  There is provided a power transmission belt which comprises a compression layer and an adhesive rubber layer which are adhered to each other by vulcanizing together and which has aramid fiber cords embedded in the adhesive rubber layer, wherein the compression layer and the adhesive rubber layer are formed of vulcanizate of an ethylene-&agr;-olefin-diene rubber compound and wherein the aramid fiber cords having a first twisting coefficient and a final twisting coefficient both in the range from 650 to 950 are adhesion treated with a resorcin-formalin-latex adhesive composition wherein the latex comprises at least one of chlorosulfonated polyethylene and alkylated chlorosulfonated polyethylene in an amount of 50-100% by weight based on the solid components of the resorcin-formalin-latex and adhered to and embedded in the adhesive rubber layer. A process for the production of such power transmission belt is also provided.

  本发明提供了一种动力传输皮带，其包括一个压缩层和一个粘合橡胶层，它们通过硫化黏合在一起，并且在粘合橡胶层中嵌入了芳纶纤维绳，其中压缩层和粘合橡胶层由乙烯-α-烯烃-二烯橡胶复合物的硫化物形成，芳纶纤维绳的第一扭曲系数和最终扭曲系数都在650至950的范围内，并且用间苯二酚-福尔马林-乳胶粘合剂组合物进行粘接处理，其中乳胶包括至少一种氯磺化聚乙烯和烷基化氯磺化聚乙烯，其占间苯二酚-福尔马林-乳胶固体成分重量的50-100％，并粘接和嵌入粘合橡胶层中。还提供了一种生产这种动力传输皮带的方法。
• Manufacturing Method of Polarizing Plate Protective Film, Polarizing Plate Protective Film, Polarizing Plate, and Liquid Crystal Display Device
  申请人：Kasahara Kenzo

  公开号：US20100239787A1

  公开（公告）日：2010-09-23

  A process for producing a cellulose-ester-resin-containing protective film for polarizers through film formation by melt casting. The protective film diminishes long-period optical unevenness and suffers no unevenness even after long-term storage. Also provided are a protective film for polarizers, a polarizer employing the film, and a liquid-crystal display. The process for producing a protective film for polarizers is a process for producing by the melt casting method a polarizer-protective film containing a cellulose ester resin. The process for producing a protective film for polarizers is characterized in that the protective film contains at least one compound selected among compounds represented by the following general formula (I) and compounds having an acrylate or methacrylate group and a phenolic hydroxy group in the same molecule and that the protective film extruded from a casting die at a draw ratio of 10-30 during film formation by melt casting is transferred while holding/pressing it between a touch roll having an elastic surface and a cooling roll.

  一种通过熔融铸造进行膜形成的生产含有纤维素酯树脂的偏光片保护膜的方法。该保护膜减少了长周期光学不均匀性，并且即使长期存储后也不会出现不均匀性。还提供了用于偏光片的保护膜，使用该膜的偏光器和液晶显示器。生产偏光片保护膜的方法是通过熔融铸造法生产含有纤维素酯树脂的偏光片保护膜的方法。生产偏光片保护膜的方法的特点在于，保护膜包含以下通式（I）所代表的化合物中选择的至少一种化合物和在同一分子中具有丙烯酸酯或甲基丙烯酸酯基和酚羟基的化合物，并且在熔融铸造过程中，通过保持/压制保护膜在具有弹性表面的触摸辊和冷却辊之间转移，以拉伸比为10-30的方式挤出保护膜。
• Method of bonding a hydrogenated nitrile rubber composition with fibers and articles
  申请人：MITSUBOSHI BELTING LTD.

  公开号：EP0440369A2

  公开（公告）日：1991-08-07

  The present invention is directed to a method wherein fibers are treated with a first, second, and third treatment solution. The third treatment solution includes a chlorinated rubber and a rubber-containing composition having acrylonitrile-butadiene rubber or hydrogenated acrylonitrile-butadiene rubber. The treated fibers are positioned contiguous, and adhered, to an unvulcanized hydrogenated acrylonitrile-butadiene rubber composition which is then vulcanized. The resulting rubber-fiber composite exhibits improved adhesion between the hydrogenated acrylonitrile-butadiene rubber composition and the fibers. Adhesion is maintained in a hot environment even if subjected to what would conventionally be considered conditions that would result in thermal deterioration under high temperature. Thus, the rubber-fiber composite exhibits enhanced durability under the severe service conditions experienced by rubber-fiber composites.

  本发明涉及一种用第一、第二和第三处理液处理纤维的方法。第三种处理液包括氯化橡胶和含有丙烯腈-丁二烯橡胶或氢化丙烯腈-丁二烯橡胶的橡胶组合物。处理过的纤维被放置在未硫化的氢化丙烯腈-丁二烯橡胶组合物上，然后进行硫化。由此产生的橡胶-纤维复合材料改善了氢化丙烯腈-丁二烯橡胶组合物与纤维之间的粘附性。在高温环境下，即使受到通常被认为会导致高温下热劣化的条件影响，粘附力也能保持不变。因此，在橡胶纤维复合材料所经历的严酷使用条件下，橡胶纤维复合材料表现出更强的耐用性。
• Flame retardant organopolysiloxane-polycarbonate triblock copolymers
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0472911A2

  公开（公告）日：1992-03-04

  Phenol-organopolysiloxane chainstoppers are phosgenated in combination with a bisphenol to make flame retardant organopolysiloxane-polycarbonate triblock copolymers. The phenol-organopolysiloxane chainstoppers can be made by effecting addition between an aliphatically unsaturated phenol and a silicon-hydride organopolysiloxane.

  苯酚-有机聚硅氧烷阻链剂与双酚结合进行磷化，可制成阻燃性有机聚硅氧烷-聚碳酸酯三嵌段共聚物。苯酚-有机聚硅氧烷阻链剂可通过脂肪族不饱和苯酚与硅氢有机聚硅氧烷之间的加成反应制成。