N-[2-(4-Hydroxyphenyl)ethyl]-2-methylpropanamide | 921607-19-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N-[2-(4-Hydroxyphenyl)ethyl]-2-methylpropanamide
• CAS: 921607-19-4
• 化学式: C₁₂H₁₇NO₂
• 分子量: 207.27
• InChiKey: QJCDVCUDEJYIRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Aptamers for C. Difficile Diagnostics
  申请人：Ochsner Urs

  公开号：US20120231467A1

  公开（公告）日：2012-09-13

  The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by Clostridium difficile ; diagnostic kits and methods comprising such aptamers; and methods of making and using such aptamers.
• Aptamers and Diagnostic Methods for Detecting the EGF Receptor
  申请人：SomaLogic, Inc.

  公开号：US20140296501A1

  公开（公告）日：2014-10-02

  The present invention provides aptamers that specifically bind to the EGF receptor in a sample, and diagnostic and analytical methods using those aptamers.
• APTAMERS AND DIAGNOSTIC METHODS FOR DETECTING THE EGF RECEPTOR
  申请人：Quest Diagnostics Investments Incorporated

  公开号：US20150086996A1

  公开（公告）日：2015-03-26

  The present invention provides aptamers that specifically bind to the EGF receptor in a sample, and diagnostic and analytical methods using those aptamers. In some embodiments, the aptamers include a 3′ cap. In some embodiments, the 3′ cap is an inverted deoxythymidine. In some embodiments the aptamers include a spacer and at least one moiety selected from the group consisting of binding pair member and a detectable label, wherein the spacer is attached to the 5′-end of the aptamer and the moiety is attached the 5′ end of the spacer. In some embodiments the spacer is hexaethylene glycol. In some embodiments, the binding pair member biotin. In some embodiments the detectable label is a fluorophore.
• Aptamers for Clostridium Difficile Diagnostics
  申请人：SOMALOGIC, INC.

  公开号：US20150125867A1

  公开（公告）日：2015-05-07

  The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by Clostridium difficile ; diagnostic kits and methods comprising such aptamers; and methods of making and using such aptamers.
• US8895241B2
  申请人：——

  公开号：US8895241B2

  公开（公告）日：2014-11-25