3-(4-Methylpyridin-1-ium-1-yl)cholest-5-ene 4-methylbenzene-1-sulfonate | 7511-84-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3-(4-Methylpyridin-1-ium-1-yl)cholest-5-ene 4-methylbenzene-1-sulfonate
• 英文别名: 1-[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-4-methylpyridin-1-ium;4-methylbenzenesulfonate
• CAS: 7511-84-4
• 化学式: C40H59NO3S
• 分子量: 634.0
• InChiKey: FEUUOFIDKWLUAH-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  9.76
• 重原子数：
  45
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  69.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION
  申请人：Aktas Bertal Huseyin

  公开号：US20120115915A1

  公开（公告）日：2012-05-10

  Compositions and methods for inhibiting translation initiation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using N,N′-diarylureas and/or N,N′-diarylthiourea compounds are described.

  本文提供了抑制翻译起始的组合物和方法。描述了使用N，N'-二芳基脲和/或N，N'-二芳基硫脲化合物治疗（1）细胞增生性疾病，（2）非增生性退行性疾病，（3）病毒感染和/或（4）与病毒感染相关的疾病的组合物、方法和试剂盒。
• N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation
  申请人：President and Fellows of Harvard College

  公开号：US20160318857A1

  公开（公告）日：2016-11-03

  Compositions and methods for inhibiting translation initiation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using N,N′-diarylureas and/or N,N′-diarylthiourea compounds are described.
• US9421211B2
  申请人：——

  公开号：US9421211B2

  公开（公告）日：2016-08-23
• US9932300B2
  申请人：——

  公开号：US9932300B2

  公开（公告）日：2018-04-03