Miniaturized 62zn/62cu generator for high concentration clinical delivery of 62cu kit formulation for the facile preparation of radiolabeled cu-bis(thiosemicarbazone)compounds
申请人:Lacy L. Jeffrey
公开号:US20060275208A1
公开(公告)日:2006-12-07
A new system accomplishes easy, interchangeable production of multiple PET radiopharmaceuticals through the use of a simplified eluant-only generator and a kit based synthesis technique employing lyophilized or freeze dried ligand. Thus, by simply switching the lyophilized ligand vial kit, any number of
62
Cu-labeled radiopharmaceuticals (
62
Cu-ligand) can be interchangeably synthesized with only one
62
Zn/
62
Cu generator.
一种新系统通过使用简化的仅洗脱剂发生器和基于冻干或冷冻干燥配体的套件合成技术,实现了多种PET放射性药物的易于交换的生产。因此,通过简单地切换冻干配体瓶套件,可以使用仅一个62Zn/62Cu发生器交替合成任意数量的62Cu标记的放射性药物(62Cu配体)。