Dec-3-ynyl(methoxy)phosphinic acid | 1051982-75-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: Dec-3-ynyl(methoxy)phosphinic acid
• CAS: 1051982-75-2
• 化学式: C₁₁H₂₁O₃P
• 分子量: 232.26
• InChiKey: CSOSSPYMWBGXJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Dec-3-ynyl(methoxy)phosphinic acid 在 (bis-collidine)bromo hexafluorophosphate 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以69%的产率得到5-Bromo-6-hexyl-2-methoxy-2-oxido-3,4-dihydrooxaphosphinin-2-ium
  参考文献：
  名称：

  Preparation of halo enol phostones by reaction of acetylenic phosphonate monoesters with (bis-collidine)halo hexafluorophosphate

  摘要：

  Reaction of non-conjugated acetylenic phosphonate monoesters with (bis-collidine) bromo and iodo hexafluorophosphates was found to lead to the formation of halo enol phostones. Depending on the size of the heterocyclic compounds formed (6-8-membered compounds), endo or a mixture of endo and exo cyclization products were obtained. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.037
• 作为产物：
  描述：

  在 sodium iodide 、 盐酸 作用下， 以 丁酮 为溶剂， 以72%的产率得到Dec-3-ynyl(methoxy)phosphinic acid
  参考文献：
  名称：

  Preparation of halo enol phostones by reaction of acetylenic phosphonate monoesters with (bis-collidine)halo hexafluorophosphate

  摘要：

  Reaction of non-conjugated acetylenic phosphonate monoesters with (bis-collidine) bromo and iodo hexafluorophosphates was found to lead to the formation of halo enol phostones. Depending on the size of the heterocyclic compounds formed (6-8-membered compounds), endo or a mixture of endo and exo cyclization products were obtained. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.06.037

文献信息

• Preparation of halo enol phostones by reaction of acetylenic phosphonate monoesters with (bis-collidine)halo hexafluorophosphate
  作者：Virginie André、Sylvie Robin、Gérard Rousseau

  DOI：10.1016/j.tetlet.2008.06.037

  日期：2008.8

  Reaction of non-conjugated acetylenic phosphonate monoesters with (bis-collidine) bromo and iodo hexafluorophosphates was found to lead to the formation of halo enol phostones. Depending on the size of the heterocyclic compounds formed (6-8-membered compounds), endo or a mixture of endo and exo cyclization products were obtained. (c) 2008 Elsevier Ltd. All rights reserved.