2-(phenyl)-3-(4-methoxyphenyl)sulphanyl-1,4-naphthalenediol | 918147-32-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(phenyl)-3-(4-methoxyphenyl)sulphanyl-1,4-naphthalenediol
• 英文别名: 2-(4-Methoxyphenyl)sulfanyl-3-phenylsulfanylnaphthalene-1,4-diol
• CAS: 918147-32-7
• 化学式: C₂₃H₁₈O₃S₂
• 分子量: 406.526
• InChiKey: YYNIFKZGXGBBCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  100
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-(phenyl)-3-(4-methoxyphenyl)sulphanyl-1,4-naphthalenediol 在 氧气 、 copper(II) acetate monohydrate 作用下， 以 甲醇 为溶剂， 反应 5.0h， 以96%的产率得到bis-2-(4-phenyl)-3-(4-methylphenyl)sulphanyl-1,4-naphthalenedione
  参考文献：
  名称：

  Synthesis of Mixed Aryl 2,3-Diarylsulphanyl-1,4-naphthoquinones

  摘要：

  The reaction of 2-arylsulphanyl-1,4-napththoquinone with aromatic thiols and sodium dithionate leads to bis-2,3-(arylsulphanyl)naphthalene-1,4-diols in high yield. Corresponding oxidized products, namely 2,3-diarylsulphanyl-1,4-naphthoquinones, are prepared in near quantitative yield by a copper(II)-catalyzed aerial oxidation reaction of bis-2,3-(arylsulphanyl)naphthalene-1,4-diols under mild condition.

  DOI：

  10.1080/00397910802528951
• 作为产物：
  描述：

  4-甲氧基苯硫酚 、 2-phenylsulfanyl-[1,4]naphthoquinone 在 sodium dithionite 、 水 作用下， 以 二氯甲烷 、 乙酸乙酯 为溶剂， 反应 6.0h， 以92%的产率得到2-(phenyl)-3-(4-methoxyphenyl)sulphanyl-1,4-naphthalenediol
  参考文献：
  名称：

  Synthesis of Mixed Aryl 2,3-Diarylsulphanyl-1,4-naphthoquinones

  摘要：

  The reaction of 2-arylsulphanyl-1,4-napththoquinone with aromatic thiols and sodium dithionate leads to bis-2,3-(arylsulphanyl)naphthalene-1,4-diols in high yield. Corresponding oxidized products, namely 2,3-diarylsulphanyl-1,4-naphthoquinones, are prepared in near quantitative yield by a copper(II)-catalyzed aerial oxidation reaction of bis-2,3-(arylsulphanyl)naphthalene-1,4-diols under mild condition.

  DOI：

  10.1080/00397910802528951

文献信息

• Synthesis of Mixed Aryl 2,3-Diarylsulphanyl-1,4-naphthoquinones
  作者：W. Marjit Singh、Jubaraj B. Baruah

  DOI：10.1080/00397910802528951

  日期：2009.3.25

  The reaction of 2-arylsulphanyl-1,4-napththoquinone with aromatic thiols and sodium dithionate leads to bis-2,3-(arylsulphanyl)naphthalene-1,4-diols in high yield. Corresponding oxidized products, namely 2,3-diarylsulphanyl-1,4-naphthoquinones, are prepared in near quantitative yield by a copper(II)-catalyzed aerial oxidation reaction of bis-2,3-(arylsulphanyl)naphthalene-1,4-diols under mild condition.