(8R,9R,10R,13S,14S)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthrene-3,17-dione

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (8R,9R,10R,13S,14S)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthrene-3,17-dione
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.4
• InChiKey: DKVSUQWCZQBWCP-KWWJQKEASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• NOVEL COMPOSITION TO INCREASE LIBIDO
  申请人：Farber Michael

  公开号：US20090017107A1

  公开（公告）日：2009-01-15

  The present invention relates to a composition for increasing testosterone physiological levels comprising a sufficient amount of at least two ketosteroid derivatives of testosterone metabolism in association with a liposomal carrier bound to a saliva-absorbing carrier, wherein said increase in testosterone levels increases libido.

  本发明涉及一种用于增加睾酮生理水平的组合物，该组合物包含足够量的至少两种睾酮代谢的酮固醇衍生物与结合到唾液吸收载体的脂质体载体，其中睾酮水平的增加会增加性欲。
• Estrogen synthesis inhibitors
  申请人：THE ROCKEFELLER UNIVERSITY

  公开号：EP0161492A2

  公开（公告）日：1985-11-21

  Invention relates to 3-methylene substituted androst-4- ene-17-oxygenated compounds substituted with various substituents at the 10β-position which are useful as inhibitors of estrogen biosynthesis.

  本发明涉及在 10β 位上被各种取代基取代的 3-亚甲基取代雄-4-烯-17-氧化合物，这些化合物可用作雌激素生物合成的抑制剂。
• NOVEL COMPOSITION TO INCREASE MUSCLE STRENGTH
  申请人：FARBER Mike

  公开号：US20080153788A1

  公开（公告）日：2008-06-26

  The present invention relates to a composition comprising a sufficient amount of at least two ketosteroid derivatives of testosterone's metabolism in association with a pharmaceutically acceptable carrier for increasing testosterone's physiological levels in a male subject.
• 5alpha-ANDROSTANE-3,6,17-TRIONE (KNELLER'S TRIONE) AND METHODS OF USE THEREFOR
  申请人：Kneller Bruce W.

  公开号：US20090306031A1

  公开（公告）日：2009-12-10

  Disclosed are compounds such as 5α-androstane-3,6,17-trione, formulations comprising said compounds, and methods of use thereof to stimulate endogenous testosterone production and improve athletic performance and libido.
• 5a-ANDROSTANE-3,6,17-TRIONE (KNELLER'S TRIONE) AND METHODS OF USE THEREFOR
  申请人：Kneller Bruce W.

  公开号：US20110034429A1

  公开（公告）日：2011-02-10

  Disclosed are compounds such as 5α-androstane-3,6,17-trione, formulations comprising said compounds, and methods of use thereof to stimulate endogenous testosterone production and improve athletic performance and libido.