三甲基-2-[(1-氧代烯丙基)氧基]丙基氯化铵 | 93919-29-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 三甲基-2-[(1-氧代烯丙基)氧基]丙基氯化铵
• 英文名称: Trimethyl-2-[(1-oxoallyl)oxy]propylammonium chloride
• 英文别名: trimethyl(2-prop-2-enoyloxypropyl)azanium;chloride
• CAS: 93919-29-0
• 化学式: C9H18ClNO2
• 分子量: 207.7
• InChiKey: SFLBDBJLRVHQLY-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.19
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Controlled release formulations coated with aqueous dispersions of acrylic polymers
  申请人：——

  公开号：US20030198673A1

  公开（公告）日：2003-10-23

  A stable solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic acrylic polymer includes a substrate including an active agent selected from the group consisting of a systemically active therapeutic agent, a locally active therapeutic agent, a disinfecting and sanitizing agent, a cleansing agent, a fragrance agent and a fertilizing agent, overcoated with an aqueous dispersion of the plasticized water-insoluble acrylic polymer. The formulation provides a stable dissolution of the active agent which is unchanged after exposure to accelerated storage conditions.

  一种稳定的固体控释制剂，其涂层来自于水分散的疏水性丙烯酸聚合物，包括底物和活性剂，所述活性剂选自系统性活性治疗剂、局部活性治疗剂、消毒和卫生剂、清洁剂、香料剂和肥料剂等组合中的一种，覆盖在塑化的水不溶性丙烯酸聚合物的水分散涂层上。该制剂提供了稳定的活性剂溶解度，在加速存储条件下暴露后仍然不变。
• MODIFIED RELEASE FORMULATIONS OF A BUPROPION SALT
  申请人：OBEREGGER Werner

  公开号：US20080038348A1

  公开（公告）日：2008-02-14

  The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.

  本发明涉及药物组合物、配方和药物，包括一种丁螺环酮盐，特别是包括有效量的丁螺环酮氢溴酸盐的缓释片剂，以及使用丁螺环酮盐来制备治疗疾病的药物。
• BUPROPION HYDROBROMIDE AND THERAPEUTIC APPLICATIONS
  申请人：WILLIAMS Parry Robert

  公开号：US20080075774A1

  公开（公告）日：2008-03-27

  Bupropion hydrobromide formulations as well as their use for the treatment of conditions is described.

  本文描述了Bupropion hydrobromide配方及其用于治疗疾病的使用。
• Modified release formulations of a bupropion salt
  申请人：Oberegger Werner

  公开号：US20070027213A1

  公开（公告）日：2007-02-01

  The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.

  本发明涉及制药组合物、配方和药物，包括丁丙腈酮盐，特别是包含有效量的丁丙腈酮羟溴盐的改良释放片剂，以及使用丁丙腈酮盐制备治疗疾病的药物。
• BUPROPION HYDROBROMIDE POLYMORPHS
  申请人：TURCHETTA Stefano

  公开号：US20100068270A1

  公开（公告）日：2010-03-18

  Polymorphous and amorphous forms of bupropion hydrobromide are described.

  描述了盐酸布洛芬的多形和无定形形式。