三甲基戊基铵 | 20064-27-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 三甲基戊基铵
• 英文名称: Trimethyl-pentyl-ammonium
• 英文别名: n-Pentyltrimethylammonium；Pentyltrimethylammonium；Trimethylpentylammonium；trimethyl(pentyl)azanium
• CAS: 20064-27-1
• 化学式: C₈H₂₀N
• 分子量: 130.254
• InChiKey: ACZOGADOAZWANS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2923900090

反应信息

• 作为反应物：
  描述：

  三甲基戊基铵 生成 N,N-二甲基戊胺
  参考文献：
  名称：

  v. Braun, Justus Liebigs Annalen der Chemie, 1911, vol. 382, p. 22

  摘要：

  DOI：

文献信息

• [EN] SYNTHETIC RECEPTOR COMPOUNDS FOR DETECTION OF MODIFIED AMINO ACIDS IN PEPTIDES AND PROTEINS<br/>[FR] COMPOSÉS RÉCEPTEURS SYNTHÉTIQUES POUR LA DÉTECTION D'ACIDES AMINÉS MODIFIÉS DANS DES PEPTIDES ET DES PROTÉINES
  申请人：UNIV NORTH CAROLINA CHAPEL HILL

  公开号：WO2017079538A1

  公开（公告）日：2017-05-11

  The present invention concerns compounds useful as probes for detecting modified amino acids in peptides or proteins.

  这项发明涉及作为探针用于检测肽或蛋白质中修饰氨基酸的化合物。
• EFTU INHIBITORS OR AMINOTHIAZOLES AND THEIR USES
  申请人：LaMarche Matthew J.

  公开号：US20080221142A1

  公开（公告）日：2008-09-11

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases.

  本申请描述了对治疗、预防和/或改善疾病有用的有机化合物。
• [EN] ONE-STEP 18F LABELING OF BIOLOGICAL SUBSTRATES AND USES OF 18F LABELED BIOLOGICAL SUBSTRATES<br/>[FR] MARQUAGE AU 18F EN UNE SEULE ÉTAPE DE SUBSTRATS BIOLOGIQUES ET UTILISATIONS DESDITS SUBSTRATS BIOLOGIQUES MARQUÉS AU 18F
  申请人：US HEALTH

  公开号：WO2012094334A1

  公开（公告）日：2012-07-12

  Disclosed is a rapid one-step 18F radiolabeling method for biological substrates that contain a specific arene group activated for nucleophilic aromatic substitution with 18F. The method involves reacting a biological substrate having at least one 4-nitro-3-trifluorobenzamide moiety covalently bonded thereto with a 18F anion in the presence of a cryptand. The method of the present invention has one or more advantages: significantly shortens reaction and overall synthesis time; requires low amount of precursor; and provides acceptable yields of high specific activity product. Also disclosed are methods of identifying a cell or population of cells expressing a protein or peptide of interest and methods for diagnosing a disease in a subject. Further disclosed are 18F labeled compounds of formula (I): wherein X, n, R1, R2, and R3 are as described herein.

  本文揭示了一种用于含有特定芳烃基团的生物底物的快速一步18F放射性标记方法，该基团被激活用于与18F进行亲核芳香取代。该方法涉及在存在cryptand的情况下，将至少有一个4-硝基-3-三氟苯甲酰基团共价键合到生物底物上的生物底物与18F阴离子反应。本发明的方法具有一个或多个优点：显著缩短了反应和整体合成时间；需要较少的前体量；并提供了高比活性产物的可接受产量。还揭示了用于识别表达感兴趣蛋白质或肽的细胞或细胞群的方法，以及用于诊断受试者疾病的方法。进一步揭示了化合物的18F标记的公式（I）：其中X，n，R1，R2和R3如本文所述。
• Sustained-release liposomal anesthetic compositions
  申请人：Kim Sinil

  公开号：US20060078606A1

  公开（公告）日：2006-04-13

  The invention provides a method for obtaining local anesthetics encapsulated in liposomes, such as multivesicular liposomes, with high encapsulation efficiency and slow release in vivo. When the encapsulated anesthetic is administered as a single intracutaneous dose, the duration of anesthesia and half-life of the drug at the local injection site is increased as compared to injection of unencapsulated anesthetic. The maximum tolerated dose of the encapsulated anesthetic is also markedly increased in the liposomal formulation over injection of unencapsulated anesthetic. These results show that the liposomal formulation of local anesthetic is useful for sustained local infiltration and nerve block anesthesia.

  该发明提供了一种获取包埋在脂质体中（如多囊脂质体）的局部麻醉药物的方法，具有高包埋效率和缓慢释放的特点。当包埋的麻醉药物作为单次皮内注射剂给予时，与未包埋麻醉药物注射相比，局部注射部位的麻醉持续时间和药物的半衰期增加。在脂质体制剂中，包埋的麻醉药物的最大耐受剂量也显著增加，而未包埋麻醉药物的注射则没有这种效果。这些结果表明，局部麻醉药物的脂质体制剂对于持续的局部浸润和神经阻滞麻醉是有用的。
• PHOSPHORIC ACID DIESTER SALT, PRODUCTION METHOD THEREFOR, NON-AQUEOUS ELECTROLYTIC SOLUTION FOR POWER STORAGE ELEMENT, AND POWER STORAGE ELEMENT
  申请人：STELLA CHEMIFA CORPORATION

  公开号：US20180237461A1

  公开（公告）日：2018-08-23

  Disclosed is a phosphoric acid diester salt which can suppress deterioration of charge-discharge characteristics of a power storage element, and can suppress the rise in internal resistance after storage at high temperature, a production method therefor, a non-aqueous electrolytic solution for a power storage element, and a power storage element. Disclosed is a phosphoric acid diester salt represented by the following chemical formula (1): wherein M n+ represents a hydrogen ion, an alkali metal ion, an alkali earth metal ion, an aluminum ion, a transition metal ion, or an onium ion; R 1 and R 2 are different from each other and represent a hydrocarbon group having 1 to 10 carbon atoms, or a hydrocarbon group having 1 to 10 carbon atoms and having at least one of a halogen atom, a heteroatom, and an unsaturated bond; and n represents a valence.

  本发明公开了一种磷酸二酯盐，可以抑制电力储存元件的充放电特性恶化，可以抑制高温储存后内阻上升，以及其生产方法、用于电力储存元件的非水电解质溶液和电力储存元件。本发明公开了一种由下式（1）表示的磷酸二酯盐：其中Mn+表示氢离子、碱金属离子、碱土金属离子、铝离子、过渡金属离子或离子离子；R1和R2不同，表示具有1至10个碳原子的烃基，或具有1至10个碳原子且具有卤素原子、杂原子和不饱和键中的至少一个的烃基；n表示价数。