丙氧基羰基丙基碳酸酯 | 43086-15-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 中文名称: 丙氧基羰基丙基碳酸酯
• 英文名称: di-n-propyl dicarbonate
• 英文别名: dipropyl dicarbonate；Di-n-propylpyrocarbonat；dicarbonic acid dipropyl ester；Dikohlensaeure-dipropylester；Pyrokohlensaeure-dipropylester；propoxycarbonyl propyl carbonate
• CAS: 43086-15-3
• 化学式: C₈H₁₄O₅
• 分子量: 190.196
• InChiKey: APGAJOXIADQGSH-UHFFFAOYSA-N

物化性质

• 沸点：
  240.4±9.0 °C(Predicted)
• 密度：
  1.093±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  丙氧基羰基丙基碳酸酯 生成 碳酸二丙酯(DPC)
  参考文献：
  名称：

  Boehm; Mehta, Chemische Berichte, 1938, vol. 71, p. 1797,1802

  摘要：

  DOI：
• 作为产物：
  描述：

  氯甲酸丙酯 、 alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 、 氯仿 作用下， 生成 丙氧基羰基丙基碳酸酯
  参考文献：
  名称：

  Boehm; Mehta, Chemische Berichte, 1938, vol. 71, p. 1797,1802

  摘要：

  DOI：

文献信息

• Synthesis of Carbonates and Related Compounds from Carbon Dioxide via Methanesulfonyl Carbonates
  作者：Mark O. Bratt、Paul C. Taylor

  DOI：10.1021/jo026753g

  日期：2003.7.1

  Carbonate anions resulting from reaction of primary or secondary alcohols with carbon dioxide, when added to methanesulfonic anhydride in cooled acetonitrile solution, yield methanesulfonyl carbonates, a new class of synthetic intermediate. Base-mediated reaction of the methanesulfonyl carbonates with alcohols, thiols, and amines yields carbonates, thiocarbonates, and carbamates, respectively. Overall

  由伯醇或仲醇与二氧化碳反应生成的碳酸根阴离子，在冷却的乙腈溶液中加到甲磺酸酐中后，会产生甲磺酰碳酸酯，这是一类新的合成中间体。甲磺酰碳酸酯与醇，硫醇和胺的碱介导反应分别产生碳酸盐，硫代碳酸盐和氨基甲酸酯。这三个步骤的总产率从19％到42％不等。
• Pesticidal 1-arylpyrazoles
  申请人：Rhone-Poulenc, Inc.

  公开号：US06350771B1

  公开（公告）日：2002-02-26

  The invention relates to novel 1-arylpyrazole oxime derivatives, of general formula (I) or (I bis) These compounds are found to be generally safe systemic insecticides for control of arthropod, nematode, helminth or protozoan pests including compositions and derivatives thereof.

  这项发明涉及新颖的1-芳基吡唑肟衍生物，通式为(I)或(I bis)。这些化合物被发现通常是安全的全身杀虫剂，用于控制节肢动物、线虫、蠕虫或原生动物害虫，包括其组合物和衍生物。
• beta-DIHYDROFURAN DERIVING COMPOUND, METHOD FOR PRODUCING beta-DIHYDROFURAN DERIVING COMPOUND OR beta-TETRAHYDROFURAN DERIVING COMPOUND, beta-GLYCOSIDE COMPOUND, METHOD FOR PRODUCING beta GLYCOSIDE COMPOUND, AND METHOD FOR PRODUCING 4'-ETHYNYL D4T AND ANALOGUE COMPOUNDS THEREOF
  申请人：Iriyama Yusuke

  公开号：US20120322995A1

  公开（公告）日：2012-12-20

  The invention provides a process for producing a β-dihydrofuran derivative represented by formula (1) or a β-tetrahydrofuran derivative represented by formula (4), characterized in that the process includes causing a dialkyl dicarbonate, a diaralkyl dicarbonate, or a halide to act on a diol compound represented by formula (2) or (3). The invention also provides a process for producing 4′-ethynyl-2′,3′-didehydro-3′-deoxythymidine or an analog thereof, the process including glycosylation and deprotection.

  该发明提供了一种生产由式（1）表示的β-二氢呋喃衍生物或由式（4）表示的β-四氢呋喃衍生物的过程，其特征在于该过程包括使二烷基二碳酸酯、二芳基二碳酸酯或卤化物作用于由式（2）或（3）表示的二醇化合物。该发明还提供了一种生产4'-乙炔基-2',3'-二去氢-3'-脱氧胸苷或其类似物的过程，包括糖基化和去保护。
• Process for selective derivatization of taxanes
  申请人：Florida State University

  公开号：EP1193262A1

  公开（公告）日：2002-04-03

  A process is described for converting the C(7) hydroxy group of a 10-acyloxy-7-hydroxytaxane to an acetal or ketal, the process comprising treating the 10-acyloxy-7-hydroxytaxane with a ketalizing agent in the presence of an acid catalyst to form a C(7) ketalized taxane of the formula or wherein either X31 or X32 represents the 10-acyloxy-7-hydroxytaxane moiety and the other of X31 and X32 as well as X33 and X34 are independently hydrocarbyl, substituted hydrocarbyl or heteroaryl moieties. Taxanes having a ketalized C(7) hydroxy group are also described.

  描述了一种将10-酰氧基-7-羟基紫杉烷的C(7)羟基团转化为缩醛或缩酮的过程，该过程包括在酸催化剂存在下用缩酮化试剂处理10-酰氧基-7-羟基紫杉烷，以形成具有以下结构的C(7)缩酮化紫杉烷，其中X31或X32代表10-酰氧基-7-羟基紫杉烷基团，而X31和X32的另一个以及X33和X34均独立地为烃基、取代烃基或杂环芳基基团。还描述了具有缩酮化C(7)羟基团的紫杉烷。
• METHOD FOR PRODUCING N-ALKOXYCARBONYLPIPERIDINE DERIVATIVE, AND INTERMEDIATE THEREFOR
  申请人：YUKI GOSEI KOGYO CO., LTD.

  公开号：US20210122729A1

  公开（公告）日：2021-04-29

  The object of the present invention is to provide a simple method for preparing an N-alkoxycarbonyl piperidine derivative. The object can be solved by a method for preparing a hydroxypiperidine derivative, comprising a step of: (A) reacting a piperidylidene acetic acid derivative represented by the formula (1): wherein R 1 is an aralkyl group which may have a substituent group, and R 2 is an alkyl group, with 4-hydroxypiperidine in the presence of base, to obtain a hydroxypiperidine derivative represented by the formula (2) or the formula (3): wherein R 1 is an aralkyl group which may have a substituent group.

  本发明的目的是提供一种制备N-烷氧羰基哌啶衍生物的简单方法。该目的可以通过制备羟基哌啶衍生物的方法来解决，包括以下步骤：（A）在碱存在下，将由式（1）表示的哌啶基乙酸衍生物与4-羟基哌啶反应，其中R1是可能带有取代基的芳基烷基，R2是烷基，以得到由式（2）或式（3）表示的羟基哌啶衍生物，其中R1是可能带有取代基的芳基烷基。