丙酰胺,2-氨基-N-(3-氰基-4,5-二甲基-1H-吡咯-2-基)- | 84807-66-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 丙酰胺,2-氨基-N-(3-氰基-4,5-二甲基-1H-吡咯-2-基)-
• 中文别名: N-[3-[3-(3-氨基丙基氨基)丙基氨基]丙基]丁烷-1,4-二胺
• 英文名称: Homocaldopentamine
• 英文别名: N'-[3-[3-(3-aminopropylamino)propylamino]propyl]butane-1,4-diamine
• CAS: 84807-66-9
• 化学式: C₁₃H₃₃N₅
• 分子量: 259.44
• InChiKey: FPTWYQKWFMIJPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  18
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  88.1
• 氢给体数：
  5
• 氢受体数：
  5

文献信息

• Processes and host cells for genome, pathway, and biomolecular engineering
  申请人：enEvolv, Inc.

  公开号：US10370654B2

  公开（公告）日：2019-08-06

  The present disclosure provides compositions and methods for genomic engineering.

  本公开提供了基因组工程的组合物和方法。
• MATERIAUX HYBRIDES ORGANIQUES-INORGANIQUES, MESOPOREUX, POUR SEPARER LES GAZ
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：EP1370563B1

  公开（公告）日：2006-09-06
• Mesoporous organic-inorganic hybrid materials for separating gases
  申请人：——

  公开号：US20040122250A1

  公开（公告）日：2004-06-24

  The invention concerns a method for preparing organic-inorganic hybrid materials with controlled porosity and functionality, comprising hydrolysis and condensation polymerisation of at least a compound of formula (I): Z—R 1 —Si(OR)(OR′)(OR″), wherein: Z represents either an atom selected among chlorine, bromine or iodine atoms, or an amino or phosphino group; R, R′ and R″, independently of one another, represent an alkyl radical comprising on to four carbon atoms; R 1 represents a divalent radical derived from an aliphatic hydrocarbon chain comprising 1 to 30 carbon atoms, wherein are optionally interspersed one or several arylene; —O—, —S—, —O—C(═O), —N(R 6 )—C(═O)— or N(R 6 ), with at least an alkaline or alkaline-earth silicate of (II) in a mol ratio (I)/(II)=1/9 in the presence of at least a non-ionic surfactant in micellar concentration, to form a mesoporous silica represented by formula (III): Z—R 1 —SiO 1,5 9 SiO 2 , whereon is then anchored an equivalent of an organic compound, represented by (&Dgr;)N—H, comprising at least a —NH— group capable of reacting with the function Z, to form a functionalised mesoporous silica represented by formula (IV): (&Dgr;)N—R—SiO 1,5 9 SiO 2 , which is optionally complexed with a metallic carbon to form an organometallic complex (V). The invention also concerns the products of formulae (IV) and (V) and their use for separating gases.
• Lfa-1 inhibitors and use thereof
  申请人：Soda Kuniyasu

  公开号：US20060281820A1

  公开（公告）日：2006-12-14

  The present invention provides an LFA-1 inhibitor comprising at least one member selected from the group consisting of polyamines represented by general formula (1) and pharmaceutical acceptable salts thereof: NH 2 —(CH 2 )m1-(NH)p1-(CH 2 )m2-(NH)p2-(CH 2 )m3-(NH)p3-(CH 2 )m4-(NH)p4-(CH 2 )m5-NH 2 (1), wherein at least two of m1 to m5 exceed 0, each of m1 to m5 is independently an integer of 0 to 7, the sum of m1+m2+m3+m4+m5 is 2 or more but less than 18, at least one of p1, p2, p3 and p4 is 1, and each of others independently represents 0 or 1. The present invention also provides a pharmaceutical composition containing the LFA-1 inhibitor and a method for the inhibition or the treatment of diseases.
• MESOPOROUS ORGANIC-INORGANIC HYBRID MATERIALS FOR SEPARATING GASES
  申请人：Corriu Robert

  公开号：US20080152561A1

  公开（公告）日：2008-06-26

  The invention concerns a method for preparing organic-inorganic hybrid materials with controlled porosity and functionality comprising hydrolysis and condensation polymerization of a compound of formula (I): Z-R 1 —Si(OR)(OR′)(OR″), with an alkaline or alkaline-earth silicate in a mol ratio of (I)/(silicate)=1:9, in the presence of a non-ionic surfactant, to form a mesoporous silica represented by Z-R 1 —SiO 1.5 9 SiO 2 , whereon is then anchored an organic compound, represented by (Δ)N—H, comprising a —NH— group capable of reacting with Z, to form a functionalized mesoporous silica represented by (Δ)N—R—SiO 1.5 9 SiO 2 , which is optionally complexed with a metallic cation to form an organometallic complex. The invention also concerns the use of these materials to separate gases.