2-(2-naphthylmethyl)-4,5-dihydrothiazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(2-naphthylmethyl)-4,5-dihydrothiazole
• 英文别名: 2-(naphthalen-2-ylmethyl)-4,5-dihydro-1,3-thiazole
• 化学式: C₁₄H₁₃NS
• 分子量: 227.33
• InChiKey: SREOLXBLUWSUDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  37.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-萘乙腈 、 巯基乙胺 以 乙醇 为溶剂， 以63%的产率得到2-(2-naphthylmethyl)-4,5-dihydrothiazole
  参考文献：
  名称：

  Synthèse, activités anti-parasitaire et anti-fongique d'arylalkyl- et d'arylvinylthiazolines

  摘要：

  Twenty-seven arylalkyl- or arylvinylthiazolines were synthesized and tested in vitro against three genera of nematodes, various yeasts and opportunistic fungi. Vinyl compounds seem to have an interesting filaricidal activity against Molinema dessetae and anti-fungal activity against yeasts.

  DOI：

  10.1016/0223-5234(93)90076-q

文献信息

• Synthèse, activités anti-parasitaire et anti-fongique d'arylalkyl- et d'arylvinylthiazolines
  作者：R Caujolle、G Baziard-Mouysset、JD Favrot、M Payard、PR Loiseau、H Amarouch、MD Linas、JP Seguela、PM Loiseau、C Bories、P Gayral

  DOI：10.1016/0223-5234(93)90076-q

  日期：1993.1

  Twenty-seven arylalkyl- or arylvinylthiazolines were synthesized and tested in vitro against three genera of nematodes, various yeasts and opportunistic fungi. Vinyl compounds seem to have an interesting filaricidal activity against Molinema dessetae and anti-fungal activity against yeasts.