乳酸TEA盐 | 20475-12-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 乳酸TEA盐
• 英文名称: Tris-(2-hydroxyethyl) ammonium lactate
• 英文别名: 2-hydroxypropanoate;tris(2-hydroxyethyl)azanium
• CAS: 20475-12-1
• 化学式: C9H21NO6
• 分子量: 239.27
• InChiKey: RJQQOKKINHMXIM-UHFFFAOYSA-N

物化性质

• 熔点：
  -54.9 °C (decomp)
• 密度：
  1.222 g/cm3(Temp: 238.1 °C Press: 3.41 Torr)
• LogP：
  -1.108 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.28
• 重原子数：
  16
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  122
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• Composition for Patch Preparation Comprising Drug, Organic Solvent, Lipophilic Mass Base, and Powder
  申请人：MEDRX CO., LTD.

  公开号：US20150174249A1

  公开（公告）日：2015-06-25

  The present disclosure provides a composition for a non-aqueous patch preparation with excellent adhesibility which can sustainedly release a drug. The patch preparation can improve the adhesibility of the patch preparation and the release property of a drug by the addition of a powder ingredient the long-time sustention of the adhesibility of tape preparations enables an improvement of the transdermal absorbability and the sustained release of a drug.

  本公开提供了一种具有良好粘附性和可持续释放药物的非水性贴剂制剂组合物。通过添加粉末成分，该贴剂制剂可以改善贴剂制剂的粘附性和药物的释放性能，贴剂制剂的长时间粘附性能有助于提高经皮吸收性和药物的持续释放。
• Water-in-oil emulsions and process for preparing them
  申请人：UNILEVER PLC

  公开号：EP0009404A2

  公开（公告）日：1980-04-02

  A high internal phase water-in-oil emulsion comprises a water soluble amino acid or a salt thereof; water; a branched chain non-polar oil; and a liquid emulsifier having an HLB value of from 1 to 7. The aqueous phase including the amino acid and a salt thereof and water will comprise from 75 to 98% by volume of the emulsion, and the oily phase including the oil and emulsifier will comprise from 2 to 25% by volume of the emulsion. The emulsions find utility particularly in cosmetics and toiletries products and in pharmaceuticals.

  高内相油包水乳剂包括水溶性氨基酸或其盐、水、支链非极性油和 HLB 值为 1 至 7 的液体乳化剂。水相包括氨基酸及其盐和水，占乳液体积的 75% 至 98%，油相包括油和乳化剂，占乳液体积的 2% 至 25%。这种乳液尤其适用于化妆品、洗浴用品和药品。
• Water-in-oil emulsions and process for preparing same
  申请人：UNILEVER PLC

  公开号：EP0047804A1

  公开（公告）日：1982-03-24

  A high internal phase water-in-oil emulsion comprises, in addition to water, a branched chain non-polar oil, a liquid emulsifier having an HLB value of from 1 to 7 and a special montmorillonite clay derivative which stabilises the emulsion. The emulsion can optionally also include a source of magnesium ions which further enhance its stability during storage. The emulsion is particularly suitable as a cosmetic cream for topical application to the skin.

  高内相油包水乳剂除水以外，还包括支链非极性油、HLB 值为 1 到 7 的液体乳化剂和可稳定乳剂的特殊蒙脱石粘土衍生物。乳液中还可以选择加入镁离子源，以进一步增强其在储存过程中的稳定性。这种乳液特别适合用作局部涂抹于皮肤的化妆品膏。
• Water in oil emulsions
  申请人：UNILEVER PLC

  公开号：EP0048153A1

  公开（公告）日：1982-03-24

  A high internal phase water-in-oil emulsion comprises, in addition to water, a branched chain non-polar oil, a non-anionic liquid emulsifier having an HLB value of from 1 to 7, and a special montmorillonite clay derivative and a water-soluble salt of magnesium which together stabilise the emulsion. The emulsion is particularly suitable as a cosmetic cream for topical application to the skin.

  高内相油包水乳剂除水以外，还包括支链非极性油、HLB 值为 1-7 的非阴离子液体乳化剂、特殊蒙脱石粘土衍生物和水溶性镁盐，它们共同稳定了乳剂。 这种乳液特别适合用作局部涂抹于皮肤的化妆膏。
• Skin treatment composition
  申请人：UNILEVER N.V.

  公开号：EP0086070A2

  公开（公告）日：1983-08-17

  A cosmetically acceptable composition for topical application to human skin comprises from 0.1 to 20% by weight of a substituted 2-hyroxyoctanoic acid or 2-ketooctanoic acid or a mixture thereof, together with an amount of a special neutralising agent sufficient to adjust the pH of the composition to a value of from 3 to 7. The special neutralising agent is one having a cation whose ionic radius is at least 100 pm.

  一种可用于人体皮肤局部的化妆品组合物，按重量计含有 0.1%至 20%的取代的 2-羟基辛酸或 2-酮辛酸或它们的混合物，以及一定量的特殊中和剂，足以将组合物的 pH 值调节到 3 至 7。特殊中和剂是一种离子半径至少为 100 pm 的阳离子。