((+)-catechol)-pentabenzoate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: ((+)-catechol)-pentabenzoate
• 英文别名: ((+)-Catechin)-pentabenzoat；(d-Catechin)-pentabenzoat；Catechin pentabenzoate；[(2R,3S)-5,7-dibenzoyloxy-2-(3,4-dibenzoyloxyphenyl)-3,4-dihydro-2H-chromen-3-yl] benzoate
• 化学式: C₅₀H₃₄O₁₁
• 分子量: 810.813
• InChiKey: RFKGHGMSJVVYTB-YWPUXERESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.7
• 重原子数：
  61
• 可旋转键数：
  16
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  141
• 氢给体数：
  0
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  苯甲酰氯 、 儿茶提取物 在 吡啶 作用下， 生成 ((+)-catechol)-pentabenzoate
  参考文献：
  名称：

  Perkin; Yoshitake, Journal of the Chemical Society, 1902, vol. 81, p. 1163

  摘要：

  DOI：

文献信息

• Perkin; Yoshitake, Journal of the Chemical Society, 1902, vol. 81, p. 1168
  作者：Perkin、Yoshitake

  DOI：——

  日期：——
• Perkin; Yoshitake, Journal of the Chemical Society, 1902, vol. 81, p. 1163
  作者：Perkin、Yoshitake

  DOI：——

  日期：——
• Methods and compositions for treating metabolic disorders
  申请人：Mootha Vamsi Krishna

  公开号：US20090143279A1

  公开（公告）日：2009-06-04

  The present invention provides methods of treating of disorders characterized by defective mitochondrial activity. In particular compounds of the present invention can be used in the treatment metabolic diseases and neurodegenerative diseases. The methods are also useful to increase oxidative phosphorylation or to decrease reactive oxygen species (ROS) production in a subject in need thereof.
• DISSOLUTION OF AMYLOID FIBRILS BY FLAVONOIDS AND OTHER COMPOUNDS
  申请人：Eisenberg David S.

  公开号：US20100048510A1

  公开（公告）日：2010-02-25

  Methods for disrupting amyloid fibrils in a subject, comprising combining an effective amount of a β-2 microglobulin fibril disrupting compound with a medium associated with the subject, are disclosed. The invention also relates to combining the β-2 microglobulin fibril disrupting compound ex vivo with the blood during dialysis treatment of an animal. It also relates to methods for determining which compounds are effective at disrupting amyloid fibrils in a medium.
• US9463195B2
  申请人：——

  公开号：US9463195B2

  公开（公告）日：2016-10-11