2,5,6,7-tetramethyl-pyrazolo[1,5-a]pyrimidin-3-ylamine hydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并嘧啶类
• 英文名称: 2,5,6,7-tetramethyl-pyrazolo[1,5-a]pyrimidin-3-ylamine hydrochloride
• 英文别名: 2,5,6,7-Tetramethylpyrazolo[1,5-a]pyrimidin-3-ylamine hydrochloride；2,5,6,7-tetramethylpyrazolo[1,5-a]pyrimidin-3-amine;hydrochloride
• 化学式: C₁₀H₁₄N₄*ClH
• 分子量: 226.709
• InChiKey: YKBUATOCJKUNPW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.97
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  56.2
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,5,6,7-tetramethyl-3-nitropyrazolo[1,5-a]pyrimidine 、 锌 在 ammonium chloride 作用下， 以 乙醇 为溶剂， 以88.2%的产率得到2,5,6,7-tetramethyl-pyrazolo[1,5-a]pyrimidin-3-ylamine hydrochloride
  参考文献：
  名称：

  Compositions for dyeing keratinous fibres, containing 3-aminopyrazolo [1,5-a]pyrimidines, method of dyeing and novel 3-aminopyrazolo [1,5-a]pyrimidines

  摘要：

  该发明涉及用于氧化染色角蛋白纤维的新型组合物，包括至少一种3-氨基吡唑并［1,5-a］-嘧啶，以及采用该组合物的染色方法，新型3-氨基吡唑并［1,5-a］-嘧啶和其制备方法。

  公开号：

  US06248137B1

文献信息

• Compositions for oxidatively dyeing keratin fibers and methods for using such compositions
  申请人：Lim Mu'Ill

  公开号：US20070209123A1

  公开（公告）日：2007-09-13

  Compositions for dyeing keratin fibers comprise (a) at least one keratin dyeing compound selected from aromatic systems which comprise at least one boronic acid or boronic ester moiety and which are capable of forming upon oxidation a nucleophile or an electrophile, (b) at least one additional keratin dyeing compound selected from the group consisting of auxiliary developers and auxiliary couplers, and (c) a cosmetically suitable medium. Methods for oxidatively dyeing keratin fibers comprise the steps of applying such compositions in the presence of an oxidizing agent and rinsing the hair. A hair coloring product in kit form comprises a first separately packaged container comprising a composition as described above and a second separately packaged container comprising an oxidizing agent.

  用于染色的组合物包括：(a)至少一种选自含有至少一个硼酸或硼酸酯基团的芳香族系统的角蛋白染料化合物，这些化合物在氧化时能够形成亲核物或亲电子物；(b)至少一种额外的角蛋白染料化合物，选自辅助显色剂和辅助偶联剂的组合；(c)一种化妆品适用的介质。氧化染角蛋白纤维的方法包括在氧化剂存在下应用这样的组合物，并冲洗头发。一种套装形式的头发染色产品包括一个第一独立包装容器，其中包含上述描述的组合物，以及一个第二独立包装容器，其中包含氧化剂。
• Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
  申请人：Lim Mu'lll

  公开号：US20060156481A1

  公开（公告）日：2006-07-20

  Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and at least one N-oxides of six-membered rings with one or two nitrogen atoms keratin dyeing compound. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  氧化染色角蛋白纤维的配方，包括适用于染色的介质和至少一种含有一个或两个氮原子的六元环N-氧化物的角蛋白染料化合物。一种氧化染色角蛋白纤维的方法，包括在氧化剂存在下施用这种配方，以足够时间发展所需的着色。
• Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof
  申请人：Bolton David Philip

  公开号：US20060032002A1

  公开（公告）日：2006-02-16

  The present invention relates to compositions for the oxidative dyeing of keratin fibres, comprising a medium suitable for dyeing and a compound 2-(amino or substituted amino)-3,5-substituted phenol compounds according to the Formula (I), as defined herein.

  本发明涉及用于氧化染毛角蛋白纤维的组合物，包括适用于染色的介质和根据此处定义的公式（I）的化合物2-（氨基或取代氨基）-3,5-取代酚化合物。
• Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof
  申请人：Dahlgren Richard Marc

  公开号：US20090282622A1

  公开（公告）日：2009-11-19

  Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and at least one 3-substituted pyrazole keratin dyeing compound and derivatives thereof. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  含有适合染色的介质和至少一种3-取代吡唑角蛋白染料化合物及其衍生物的角蛋白氧化染色组合物。一种角蛋白氧化染色的方法，包括在氧化剂存在下应用这种组合物，以便在足够的时间内发展所需的着色。
• Compositions for dyeing keratinous fibres, containing 3-aminopyrazolo[1,5-a]pyrimidines, method of dyeing, and novel 3-aminopyrazolo[1,5-a]pyrimidines
  申请人：L'Oreal S.A.

  公开号：US20010020310A1

  公开（公告）日：2001-09-13

  The invention relates to novel compositions for the oxidation dyeing of keratinous fibres, comprising at least one 3-aminopyrazolo[1,5-a]-pyrimidine, to the method of dyeing which employs this composition, to novel 3-aminopyrazolo[1,5-a]pyrimidines and to the process for their preparation.

  本发明涉及一种新型组合物，用于氧化染色角蛋白纤维，包括至少一种3-氨基吡唑并[1,5-a]-嘧啶，以及采用该组合物进行染色的方法，还涉及新型3-氨基吡唑并[1,5-a]嘧啶和其制备过程。