triallylurea

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: triallylurea
• 英文别名: 1,1,3-tris(prop-2-enyl)urea
• 化学式: C₁₀H₁₆N₂O
• 分子量: 180.25
• InChiKey: MIWFTEHTSPFLKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-异氰酸丙烯 、 二烯丙基胺 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 triallylurea
  参考文献：
  名称：

  Co-crosslinker systems for encapsulation films comprising urea compounds

  摘要：

  第一组成物（A）包含（i）至少一种从三烯基异氰酸酯、三烯基氰酸酯组成的化合物（I），其中化合物（I）最好是三烯基异氰酸酯；和（ii）至少一种脲类化合物。第二组成物（B）包含第一组成物（A）和至少一种聚烯烃共聚物。组成物（B）用于生产用于封装电子设备的膜，特别是太阳能电池。

  公开号：

  US09587061B2

文献信息

• [EN] FUNCTIONALIZED NUCLEOTIDE DERIVATIVES<br/>[FR] DERIVES DE NUCLEOTIDES FONCTIONNALISES
  申请人：UNIV SYDDANSK

  公开号：WO2004106356A1

  公开（公告）日：2004-12-09

  A nucleotide derivative is disclosed, which in its 4' and/or 5' position on the sugar moiety is substituted with a group comprising a non-aromatic cyclid group comprising at least one nitrogen atom, said cyclid group optionally being substituted. The nucleotide monomer induces increased thermal stability of RNA:DNA, RNA:RNA or DNA:DNA duplexes, if said RNA and/or DNA strand comprises at least one said monomer. The nucleotides and oligonucleotides comprising at least one of said nucleotides can be used in therapy (such as antisense or antigene therapy) and in methods for synthesising polynucleotides (e.g. as a primer). The nucleotide derivative may also be used in a medicament. Further, the use of the nucleotide derivative for the preparation of a medicament for the treatment of diseases or disorders is also disclosed.

  本发明公开了一种核苷酸衍生物，其中在糖基上的4'和/或5'位置被取代为包含至少一个氮原子的非芳香环状基团，该环状基团可以被取代。如果RNA和/或DNA链中至少包含一个该单体，则该核苷酸单体能够诱导RNA：DNA，RNA：RNA或DNA：DNA双链的热稳定性增加。包括至少一个该核苷酸的核苷酸和寡核苷酸可以用于治疗（如反义或抗基因治疗）以及用于合成多核苷酸的方法（例如作为引物）。该核苷酸衍生物也可以用于药物。此外，本发明还公开了将该核苷酸衍生物用于制备治疗疾病或障碍的药物的用途。
• CO-CROSSLINKER SYSTEMS FOR ENCAPSULATION FILMS COMPRISING UREA COMPOUNDS
  申请人：ULBRICHT Daniel

  公开号：US20160177013A1

  公开（公告）日：2016-06-23

  A first composition (A) contains (i) at least one compound (I) selected from the group consisting of triallyl isocyanurate, and triallyl cyanurate, wherein the compound (I) is preferably triallyl isocyanurate; and (ii) at least one urea compound. A second composition (B) contains the first composition (A) and at least one polyolefin copolymer. Composition (B) is used for producing a film for encapsulating an electronic device, in particular a solar cell.

  第一种组合物（A）包含（i）至少一种从三烯基异氰酸酯和三烯基氰酸酯组成的化合物（I），其中化合物（I）最好是三烯基异氰酸酯；和（ii）至少一种脲化合物。第二种组合物（B）包含第一种组合物（A）和至少一种聚烯烃共聚物。组合物（B）用于生产用于封装电子设备的薄膜，特别是太阳能电池。
• 1,4-Dihydropyridine derivatives useful against tumour cells
  申请人：Ajinomoto Co., Inc.

  公开号：EP0511790A1

  公开（公告）日：1992-11-04

  Compounds of formula 1 and pharmaceutically acceptable salts thereof, wherein each of R¹,R²,R³,R⁴ and R⁵ independently represents a hydrogen atom, a lower alkyl group having 1 to 3 carbon atoms, a hydroxy group, a lower alkyloxy group having 1 to 3 carbon atoms, or a nitro group, or two substituents adjacent to each other on the benzene ring are combined together to form an alkylenedioxy group having 1 to 3 carbon atoms;    at least one of R⁶ and R⁷ represents an alkyloxycarbonyl group or an alkylaminocarbonyl group in which the alkyl moiety has a nitrogen-containing substituent and where only one of R⁶ and R⁷ represents an alkyloxycarbonyl group or an alkylaminocarbonyl group in which the alkyl group has a nitrogen-containing substituent, the other is an alkyloxycarbonyl group;    each of R⁸ and R⁹ independently represents a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms;    n represents an integer of 2 to 9;    X represents a methylene group or oxygen atom, wherein the methylene is optionally substituted with a lower alkyl group having 1 to 5 carbon atoms, or a lower alkyloxy group having 1 to 5 carbon atoms; and,    R¹⁰ represents an aryl group or an aralkyl group, wherein the aryl moiety in the aryl group and aralkyl group is optionally substituted with a substituent selected from a halogen atom, a lower alkyl group having 1 to 5 carbon atoms, a lower alkyloxy group having 1 to 5 carbon atoms, a hydroxy group an aryl group, an aryloxy group, an aralkyl group, or an aralkyloxy group, or two substituents adjacent to each other on the benzene ring are combined together to form an alkylenedioxy group having 1 to 3 carbon atoms; are effective at reducing the resistance of cancer cells which have acquired resistance to chemotherapeutic agents used in cancer treatment.

  式 1 的化合物 及其药学上可接受的盐，其中 R¹、R²、R³、R⁴ 和 R⁵ 各自独立地代表氢原子、具有 1 至 3 个碳原子的低级烷基、羟基、具有 1 至 3 个碳原子的低级烷氧基或硝基，或苯环上相邻的两个取代基结合在一起形成具有 1 至 3 个碳原子的亚烷基二氧基； R⁶ 和 R⁷ 中至少有一个代表烷氧基羰基或烷基氨基羰基，其中烷基具有含氮取代基；如果 R⁶ 和 R⁷ 中只有一个代表烷氧基羰基或烷基氨基羰基，其中烷基具有含氮取代基，则另一个代表烷氧基羰基； R⁸ 和 R⁹ 各自独立地代表氢原子或具有 1 至 5 个碳原子的低级烷基； n 代表 2 至 9 的整数； X 代表亚甲基或氧原子，其中亚甲基任选被具有 1 至 5 个碳原子的低级烷基或具有 1 至 5 个碳原子的低级烷氧基取代；以及 R¹⁰ 代表芳基或芳烷基，其中芳基和芳烷基中的芳基任选被选自卤素原子、具有 1 至 5 个碳原子的低级烷基或具有 1 至 5 个碳原子的低级烷氧基的取代基取代、1至5个碳原子的低级烷氧基、羟基、芳基、芳氧基、烷基或芳氧基，或苯环上相邻的两个取代基结合在一起形成1至3个碳原子的亚烷基二氧基； 能有效降低已对用于癌症治疗的化疗药物产生抗药性的癌细胞的抗药性。
• US3950569A
  申请人：——

  公开号：US3950569A

  公开（公告）日：1976-04-13
• US5292757A
  申请人：——

  公开号：US5292757A

  公开（公告）日：1994-03-08