倍他米松21-乙酸酯17-丙酸酯 | 5514-81-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 中文名称: 倍他米松21-乙酸酯17-丙酸酯
• 中文别名: 倍他米松21醋酸17丙酸
• 英文名称: Betamethasone 21-Acetate 17-Propionate
• 英文别名: [(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-acetyloxyacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
• CAS: 5514-81-8
• 化学式: C₂₇H₃₅FO₇
• 分子量: 490.6
• InChiKey: KJYZDNSUFNSFOL-JLWJLQCMSA-N

物化性质

• 熔点：
  115 - 123°C
• 溶解度：
  可溶于氯仿（轻微）、二恶烷（轻微）、甲醇（轻微）

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  35
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  107
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• 21-SUBSTITUTED STEROID COMPOUND
  申请人：NISSIN SHOKUHIN KABUSHIKI KAISHA

  公开号：EP0721956B1

  公开（公告）日：2000-08-02
• STENT
  申请人：Anzai Takao

  公开号：US20120197385A1

  公开（公告）日：2012-08-02

  Provided is a stent wherein the water-swellable polymer fine particles applied thereto rarely peel off even when the stent is deformed or when the water-swellable polymer fine particles are swollen. A stent wherein a plurality of water-swellable polymer fine particles are chemically fixed on the stent surface in a dispersed state is provided.
• TOPICAL FORMULATIONS COMPRISING A STEROID
  申请人：Dr. Reddy's Laboratories Ltd.

  公开号：US20160361325A1

  公开（公告）日：2016-12-15

  The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.
• US8858618B2
  申请人：——

  公开号：US8858618B2

  公开（公告）日：2014-10-14
• US9655907B2
  申请人：——

  公开号：US9655907B2

  公开（公告）日：2017-05-23