ethylamine pentafluoropropionate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 甲亚胺酸及其衍生物
• 英文名称: ethylamine pentafluoropropionate
• 英文别名: Ethylamine, N-pentafluoropropionyl-；N-ethyl-2,2,3,3,3-pentafluoropropanamide
• 化学式: C₅H₆F₅NO
• 分子量: 191.101
• InChiKey: JQRSHLBWYOGCRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  五氟丙酸酐 、 乙胺 以 乙酸乙酯 为溶剂， 反应 0.33h， 生成 ethylamine pentafluoropropionate
  参考文献：
  名称：

  Further studies on a site-specific hydrogen transfer observed in electron capture negative ion chemical ionization mass spectrometry of hydroxyamine pentafluoropropionate derivatives

  摘要：

  AbstractFurther studies have demonstrated that the site‐specific hydrogen transfer process involved in the formation of the m/z 145 anion of β‐hydroxyamine pentafluoropropionate (PFP) derivatives observed under electron capture negative ion chemical ionization conditions occurs when the two functional groups are separated by up to five carbon atoms. Deuterium labelling has established that the site specificity, transfer of a hydrogen atom from the carbon adjacent to nitrogen to the OPFP group, is maintained in 4‐amino‐butan‐1‐ol‐N, O‐(PFP)2. The corresponding PFP derivatives of the N‐methylaminoalkanol‐(PFP)2 derivatives lack the m/z 145 species with m/z 163, [OPFP]− being the base anion. Substitution of alkyl groups on the carbon adjacent to oxygen results in a diminution of the ion intensity at m/z 145. with a marked increase in the intensity of m/z 144. The formation of the m/z 145 and 144 anions to proposed to proceed through the intervention of a fluoride ion‐molecule complex as outlined in Scheme 1 with the product ion distribution dependent on which of the two pathways is preferred.

  DOI：

  10.1002/oms.1210201002

文献信息

• Reactions of poly(hexafluoropropylene oxide) perfluoroisopropyl ketone with various amines
  作者：Jon L. Howell、Chadron M. Friesen、Krista L. Laugesen、Alice E. van der Ende

  DOI：10.1016/j.jfluchem.2007.10.006

  日期：2008.3

  The reaction of poly(hexafluoropropylene oxide) perfluoroisopropyl ketone, perfluoroethyl perfluoroisopropyl, or bis-perfluoroisopropyl ketone with various amines has been studied and the products identified. A comparison of the reactivity of the ketones with different amines is made and identified by mass spectroscopy. The reaction of diethyl amine with all three ketones leads to two unexpected products

  研究了聚（六氟环氧丙烷）全氟异丙基酮，全氟乙基全氟异丙基或双全氟异丙基酮与各种胺的反应并鉴定了产物。进行了酮与不同胺的反应性的比较，并通过质谱法进行了鉴定。二乙胺与所有三个酮的反应会生成两个意想不到的产物，并考虑了它们的形成机理。