单乙基胆碱 | 13205-69-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 单乙基胆碱
• 英文名称: Monoethylcholine
• 英文别名: ethyl-(2-hydroxyethyl)-dimethylazanium
• CAS: 13205-69-1
• 化学式: C6H16NO+
• 分子量: 118.2
• InChiKey: VKHSBLZDXXEWNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• IONIC COMPOUNDS HAVING A SILYLOXY GROUP
  申请人：HYDRO-QUÉBEC

  公开号：US20150093655A1

  公开（公告）日：2015-04-02

  There is provided an ionic compound having attached thereto a silyloxy group. There is also provided methods of making this ionic compound as well as electrolytes, electrochemical cells and capacitors comprising this ionic compound.

  提供了一种具有硅氧基团的离子化合物。还提供了制备该离子化合物的方法，以及包含该离子化合物的电解质、电化学电池和电容器。
• AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE
  申请人：Shanghai Institute of Materia Medica, Chinese Academy of Sciences

  公开号：EP2725024A1

  公开（公告）日：2014-04-30

  The present invention relates to the filed of pharmarcutical chemistry, and in particular, to a novel class of azole compounds represented by general formula (I), (II) or (III) amd a preparation method thereof, a pharmarcutical composition with the compounds as active components, and a use of the azole compounds and the pharmarcutical composition in the preparation of a medicament for treatment of diseases associated with Lp-PLA2 enzyme activities, wherein each substituent is as deinfed in the specifictaion.

  本发明涉及药物化学领域，特别是一种由一般式（I）、（II）或（III）表示的新型类唑化合物，以及其制备方法，以这些化合物为活性成分的药物组合物，以及在制备用于治疗与Lp-PLA2酶活性相关疾病的药物中使用这些唑化合物和药物组合物的用途，其中每个取代基如规范中所定义。
• Industrial process for production of dialkyl carbonate and diol
  申请人：Fukuoka Shinsuke

  公开号：US20090105494A1

  公开（公告）日：2009-04-23

  It is an object of the present invention, when producing a dialkyl carbonate and a diol industrially in a large amount (e.g. not less than 2 ton/hr for the dialkyl carbonate and not less than 1.3 ton/hr for the diol) through a reactive distillation system of taking a cyclic carbonate and an aliphatic monohydric alcohol as starting materials, continuously feeding the starting materials into a continuous multi-stage distillation column in which a catalyst is present, and carrying out reaction and distillation simultaneously in the column, is to provide a specific process that enables the dialkyl carbonate and the diol to be produced each with high selectivity and high productivity stably for a prolonged period of time (e.g. not less than 1000 hours, preferably not less than 3000 hours, more preferably not less than 5000 hours), and moreover enables the dialkyl carbonate produced to be separated out and purified stably for a prolonged period of time with high efficiency. It has been discovered that by carrying out reactive distillation using a continuous multi-stage distillation column A having a specified structure, and subjecting a column top component A T thus obtained to separation by distillation using a continuous multi-stage distillation column B having a specified structure, a dialkyl carbonate of high purity (e.g. not less than 97%, preferably not less than 99%, more preferably not less than 99.9%, yet more preferably not less than 99.99%) and a diol can be produced each with a high selectivity of not less than 95%, preferably not less than 97%, more preferably not less than 99%, on an industrial scale of not less than 2 ton/hr, preferably not less than 3 ton/hr, more preferably not less than 4 ton/hr, for the dialkyl carbonate, and not less than 1.3 ton/hr, preferably not less than 1.95 ton/hr, more preferably not less than 2.6 ton/hr, for the diol, with a high yield stably for a prolonged period of time of not less than 1000 hours, preferably not less than 3000 hours, more preferably not less than 5000 hours, from a cyclic carbonate and an aliphatic monohydric alcohol.

  本发明的目的是在通过采用环碳酸酯和脂肪族一元醇作为起始原料，在连续多级蒸馏塔中连续供给起始原料，其中存在催化剂，并在该塔中同时进行反应和蒸馏的反应蒸馏系统中，工业化大量生产二烷基碳酸酯和二元醇（例如，二烷基碳酸酯不少于2吨/小时，二元醇不少于1.3吨/小时），提供一种特定的工艺，使得二烷基碳酸酯和二元醇能够在较长时间内（例如，不少于1000小时，最好不少于3000小时，更好不少于5000小时）具有高选择性和高生产率稳定地生产，并且使得生产的二烷基碳酸酯能够在较长时间内以高效率稳定地分离和纯化。发现通过采用具有特定结构的连续多级蒸馏塔A进行反应蒸馏，并将由此获得的塔顶组分AT经由具有特定结构的连续多级蒸馏塔B进行蒸馏分离，可以在不少于2吨/小时的工业规模上，对二烷基碳酸酯和二元醇分别具有不低于95%的高选择性（最好不低于97%，更好不低于99%），对于二烷基碳酸酯，产量不低于2吨/小时，最好不低于3吨/小时，更好不低于4吨/小时，对于二元醇，产量不低于1.3吨/小时，最好不低于1.95吨/小时，更好不低于2.6吨/小时，能够在不少于1000小时的较长时间内稳定地高产。
• FIRE RESISTANT GLAZINGS
  申请人：Varma Karikath Sukumar

  公开号：US20120263903A1

  公开（公告）日：2012-10-18

  An additive for alkali metal silicate solutions, comprising a quaternary ammonium compound having the general formula ( 1 ) R 1 R 2 R 3 R 4 N + OH − , wherein R 1 , R 2 , R 3 and R 4 which may be the same or different represent alkyl groups, hydroxy-substituted alkyl groups, alkaryl groups, hydroxy-substituted alkaryl groups comprising from 1 to 12 carbon atoms, or groups having the general formula —[CH 2 ]n-N + R 5 R 6 R 7 wherein n is an integer having a value of from 1 to 12, the group —[CH 2 ]n may be hydroxy-substituted, and R 5 , R 6 and R 7 which may be the same or different represent alkyl groups, hydroxy-substituted alkyl groups, alkaryl groups or hydroxy-substituted alkaryl groups comprising from 1 to 12 carbon atoms; with the proviso that at least one of the groups R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 represents a hydroxy-substituted alkyl group or a hydroxy-substituted alkaryl group comprising at least 2 carbon atoms wherein the hydroxy substituent is not located on a carbon atom which is bonded to a nitrogen atom.

  一种用于碱金属硅酸盐溶液的添加剂，包括具有一般式（1）R1R2R3R4N+OH−的季铵化合物，其中R1、R2、R3和R4（可以相同也可以不同）代表烷基基团、羟基取代的烷基基团、烷基芳基基团、羟基取代的烷基芳基基团，包括1至12个碳原子，或具有一般式—[CH2]n-N+R5R6R7，其中n为1至12的整数，基—[CH2]n可以是羟基取代的，R5、R6和R7（可以相同也可以不同）代表烷基基团、羟基取代的烷基基团、烷基芳基基团或羟基取代的烷基芳基基团，包括1至12个碳原子；但其中至少一个R1、R2、R3、R4、R5、R6和R7代表至少含有2个碳原子的羟基取代的烷基基团或羟基取代的烷基芳基基团，其中羟基取代物不位于与氮原子键合的碳原子上。
• Base Stable Ionic Liquids
  申请人：Earle Martyn J.

  公开号：US20090216015A1

  公开（公告）日：2009-08-27

  The present invention relates to novel base stable ionic liquids and uses thereof as solvents in chemical reactions, especially base catalysed chemical reactions and reactions comprising the use of strong basis.

  本发明涉及新型稳定碱基的离子液体及其在化学反应中的用途，特别是在碱催化化学反应和涉及强碱使用的反应中作为溶剂的用途。