hirtusneanine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: hirtusneanine
• 化学式: C₃₄H₃₆O₁₃
• 分子量: 652.652
• InChiKey: NMGQBHNDXOSTQJ-FIRGKESSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.85
• 重原子数：
  47.0
• 可旋转键数：
  3.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  220.51
• 氢给体数：
  7.0
• 氢受体数：
  13.0

反应信息

• 作为反应物：
  描述：

  hirtusneanine 在 potassium permanganate 作用下， 以 sodium hydroxide 为溶剂， 反应 48.0h， 以65%的产率得到(R)-(+)-甲基丁二酸
  参考文献：
  名称：

  Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen Usnea hirta

  摘要：

  Hirtusneanoside, a new O-deoxyglycoside of a dimeric tetrahydroxanthone, was isolated from the lichen Usnea hirta. Its structure, including the absolute configuration, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, ID and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure comprising L-rhamnopyranoside of a tetrahydroxanthone dimer and showed growth inhibitory activities against Gram-positive bacteria.

  DOI：

  10.1021/np070079m
• 作为产物：
  描述：

  hirtusneanoside 在 hesperidinase (EC 3.2.1.40) 作用下， 以 acetate buffer 为溶剂， 反应 48.0h， 以96.1%的产率得到hirtusneanine
  参考文献：
  名称：

  Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen Usnea hirta

  摘要：

  Hirtusneanoside, a new O-deoxyglycoside of a dimeric tetrahydroxanthone, was isolated from the lichen Usnea hirta. Its structure, including the absolute configuration, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, ID and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure comprising L-rhamnopyranoside of a tetrahydroxanthone dimer and showed growth inhibitory activities against Gram-positive bacteria.

  DOI：

  10.1021/np070079m

文献信息

• Hirtusneanoside, an Unsymmetrical Dimeric Tetrahydroxanthone from the Lichen <i>Usnea hirta</i>
  作者：Tomáš Rezanka、Karel Sigler

  DOI：10.1021/np070079m

  日期：2007.9.1

  Hirtusneanoside, a new O-deoxyglycoside of a dimeric tetrahydroxanthone, was isolated from the lichen Usnea hirta. Its structure, including the absolute configuration, was determined by means of extensive spectroscopic data (UV, IR, MS, CD, ID and 2D NMR) and chemical degradation. Hirtusneanoside has a unique structure comprising L-rhamnopyranoside of a tetrahydroxanthone dimer and showed growth inhibitory activities against Gram-positive bacteria.