trans-1-chloro-2-iodomethylcyclohexane

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: trans-1-chloro-2-iodomethylcyclohexane
• 化学式: C₇H₁₂ClI
• 分子量: 258.53
• InChiKey: QSVCCKFWAIDKCB-NKWVEPMBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.22
• 重原子数：
  9.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为产物：
  描述：

  双环[4.1.0]庚烷 在 potassium dichloroiodate 作用下， 以 氯仿 为溶剂， 以10%的产率得到trans-1-chloro-2-iodomethylcyclohexane
  参考文献：
  名称：

  Reactions of cyclopropanes with potassium dihaloiodates

  摘要：

  Reactions of potassium dihaloiodates with arylcyclopropanes and polycyclic compounds containing a cyclopropane fragment characterized by different degrees of strain lead to formation of mixed 1,3-halogenation products. If iodohalogenation should give rise to products having a iodine atom in the benzylic position, 1,3-dichloro or 1,3-dibromo derivatives are formed. Iodohalogenation of exo-tricyclo[3.2.1.0(2,4)]octane is stereoselective and is accompanied by Wagner-Meerwein rearrangement.

  DOI：

  10.1134/s1070428011030031

文献信息

• Reactions of cyclopropanes with potassium dihaloiodates
  作者：N. V. Zyk、A. Yu. Gavrilova、O. B. Bondarenko、O. A. Mukhina、V. N. Tikhanushkina

  DOI：10.1134/s1070428011030031

  日期：2011.3

  Reactions of potassium dihaloiodates with arylcyclopropanes and polycyclic compounds containing a cyclopropane fragment characterized by different degrees of strain lead to formation of mixed 1,3-halogenation products. If iodohalogenation should give rise to products having a iodine atom in the benzylic position, 1,3-dichloro or 1,3-dibromo derivatives are formed. Iodohalogenation of exo-tricyclo[3.2.1.0(2,4)]octane is stereoselective and is accompanied by Wagner-Meerwein rearrangement.