4-methoxyphenyl 1-naphthoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-methoxyphenyl 1-naphthoate
• 英文别名: 1-Naphthoic acid, 4-methoxyphenyl ester；(4-methoxyphenyl) naphthalene-1-carboxylate
• 化学式: C₁₈H₁₄O₃
• 分子量: 278.307
• InChiKey: ILRFBNJKBMHNJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-甲硫基萘 在 C₃₉H₃₂OP₂*C₁₃H₁₂N^(1-)*Pd⁽²⁺⁾*CH₃O₃S^(1-) 、 N,N-二异丙基乙胺 作用下， 以 1,2-二氯乙烷 、 甲苯 为溶剂， 65.0~110.0 ℃ 、101.33 kPa 条件下， 反应 24.0h， 生成 4-methoxyphenyl 1-naphthoate
  参考文献：
  名称：

  Palladium-Catalyzed Alkoxycarbonylation of Arylsulfoniums

  摘要：

  Alkoxycarbonylation of arylsulfoniums has been developed with the aid of a catalytic amount of a palladium-Xantphos complex under an atmospheric pressure of CO gas. Various functional groups such as carbonyl, cyano, halo, and sulfonyl groups were well tolerated under the present catalysis. Since aryldimethylsulfoniums were readily prepared from the corresponding aryl methyl sulfides and methyl triflate, one-pot alkoxycarbonylation of aryl methyl sulfides could be accomplished.

  DOI：

  10.1021/acs.orglett.9b00067

文献信息

• Palladium-catalyzed carbonylative transformation of phenols via in-situ triflyl exchangement
  作者：Hai Wang、Youcan Zhang、Chong-Liang Li、Xiao-Feng Wu

  DOI：10.1016/j.jcat.2020.06.034

  日期：2020.9

  Phenols are attractive starting materials due to their ready availability. Herein, we developed a novel method on palladium-catalyzed alkoxycarbonylation of phenols. By using commercially available Pd(OAc)(2) and PtBu center dot HBF4 as the catalyst system and aryl triflates as triflyl source to activate the other phenol, various carboxylic acid esters were prepared in moderate to good yields via Tf exchange and then O-Tf bond cleavage. Notably, phenols generated from aryl triflates after Tf transfer or other additional aliphatic alcohols can all be employed as nucleophiles to synthesize the corresponding esters. (C) 2020 Elsevier Inc. All rights reserved.
• Palladium-Catalyzed Alkoxycarbonylation of Arylsulfoniums
  作者：Hiroko Minami、Keisuke Nogi、Hideki Yorimitsu

  DOI：10.1021/acs.orglett.9b00067

  日期：2019.4.19

  Alkoxycarbonylation of arylsulfoniums has been developed with the aid of a catalytic amount of a palladium-Xantphos complex under an atmospheric pressure of CO gas. Various functional groups such as carbonyl, cyano, halo, and sulfonyl groups were well tolerated under the present catalysis. Since aryldimethylsulfoniums were readily prepared from the corresponding aryl methyl sulfides and methyl triflate, one-pot alkoxycarbonylation of aryl methyl sulfides could be accomplished.