N,N'-bis-(2'-hydroxyethyl)-p-phenylenediamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-bis-(2'-hydroxyethyl)-p-phenylenediamine
• 英文别名: N,N'-bis(2-hydroxyethyl)-p-phenylenediamine；2-({4-[(2-Hydroxyethyl)amino]phenyl}amino)ethan-1-ol；2-[4-(2-hydroxyethylamino)anilino]ethanol
• 化学式: C₁₀H₁₆N₂O₂
• mdl: MFCD20664238
• 分子量: 196.249
• InChiKey: FCDKGTXZKZEBPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  64.5
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  对苯二胺 、 2-氯乙醇 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 N,N'-bis-(2'-hydroxyethyl)-p-phenylenediamine
  参考文献：
  名称：

  Electrochemical assay method and novel p-phenylenediamine compound

  摘要：

  公开号：

  EP0663446B1

文献信息

• Synthesis of β-Amino Alcohols from Aromatic Amines and Alkylene Carbonates Using Na-Y Zeolite Catalyst
  作者：Sunil Gupte、Raghunath Chaudhari、Anandkumar Shivarkar

  DOI：10.1055/s-2006-939697

  日期：2006.6

  A simple, efficient, and environmentally benign methodology for the synthesis of β-amino alcohols from aromatic amines and alkylene carbonates in the presence of the highly active and reusable solid base catalyst Na-Y zeolite is demonstrated.

  证明了在高活性和可重复使用的固体碱催化剂 Na-Y 沸石存在下，从芳香胺和碳酸亚烷基酯合成 β-氨基醇的简单、有效和环境友好的方法。
• Hair treatment composition
  申请人：UNILEVER PLC

  公开号：EP0146350A2

  公开（公告）日：1985-06-26

  @ A product for colouring and simultaneously conditioning the hair comprises two separately packaged components, an oxidiser and a base, which are intended to be mixed before application to the hair. The oxidiser component includes an oxidising agent and a mono-long-chain quaternary ammonium conditioning agent, and the base component includes an oxidation hair dye intermediate and ammonia to adjust the pH of the base component to a value of from 10 to 12.

  一种用于染发并同时调理头发的产品包括两种独立包装的成分，一种是氧化剂，另一种是基剂，这两种成分需要在涂抹头发之前混合。氧化剂成分包括一种氧化剂和一种单长链季铵盐调理剂，基质成分包括一种氧化染发剂中间体和氨，用于将基质成分的 pH 值调节到 10 至 12。
• Hydroxyl functionalized polyetheramines as barrier packaging for oxygen-sensitive materials
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0479445A2

  公开（公告）日：1992-04-08

  Polyetheramines having improved barrier to oxygen are normally solid, thermoplastic polyethers having aromatic ether/amine repeating units in their backbones and pendent hydroxyl and amido moieties. Such polyetheramines are prepared by reacting diglycidyl ethers of dihydric aromatic compounds such as the diglycidyl ether of bisphenol A with amines having no more than two amine hydrogen such as piperazine or ethanolamine.

  具有更好氧气阻隔性的聚醚胺通常是固态的热塑性聚醚，其骨架中具有芳香族醚/胺重复单元和下垂的羟基和氨基。这种聚醚胺是由二水芳香族化合物（如双酚 A 的二缩水甘油醚）的二缩水甘油醚与哌嗪或乙醇胺等具有不超过两个胺氢的胺反应制备而成。
• Oxidation dyeing process using a composition comprising a monoaminobenzene and a metal catalyst
  申请人：L'OREAL

  公开号：US10251827B2

  公开（公告）日：2019-04-09

  The invention relates to a process for dyeing keratin fibers, comprising the use of one or more metal catalysts and of a composition (A) comprising: —one or more oxidizing agents, and —at least one monoaminobenzene of formula (I), or an addition salt or solvate thereof in which the radicals R1 to R5 represent, independently of each other: a hydrogen atom; a halogen atom, a C1-C6 alkyl radical, a C1-C6 alkoxy radical, a carboxylic radical (—COOH), a sulfonic radical (—S03 H); two of the adjacent radicals R1 to R5 possibly forming, with the carbon atoms that bear them, a saturated or unsaturated 5- to 7-membered ring, optionally comprising from 1 to 2 heteroatoms, preferably oxygen, the said ring being optionally fused with a saturated or unsaturated 5- to 6-membered ring; on condition that at least one of the radicals R1 to R5 represents an optionally substituted alkoxy radical and preferably at least one of the other radicals R1 to R5 is a hydrogen atom.

  本发明涉及一种角蛋白纤维染色工艺，包括使用一种或多种金属催化剂和一种组合物（A），组合物（A）包括： -一种或多种氧化剂，和 -至少一种式（I）的单胺苯，或其加成盐或溶液，其中自由基 R1 至 R5 各自代表：氢原子、卤素原子、C1-C6 烷基、C1-C6 烷氧基、羧基 (-COOH)、磺酸基 (-S03 H)；R1 至 R5 中相邻的两个基团可与含有它们的碳原子形成饱和或不饱和的 5 至 7 元环，可选择包含 1 至 2 个杂原子，最好是氧，所述环可选择与饱和或不饱和的 5 至 6 元环融合；条件是 R1 至 R5 自由基中至少有一个代表任选取代的烷氧基，且 R1 至 R5 自由基中至少有一个是氢原子。
• Method for the simultaneous permanent shaping and dyeing of keratinic fibers
  申请人：Henkel AG & Co. KGaA

  公开号：US10219994B2

  公开（公告）日：2019-03-05

  A method for the permanent shaping and color modification of keratinic in a single process includes the following steps. First, an aqueous composition, including at least one keratin-reducing compound and at least one alkalizing agent, is applied to the keratinic fibers and is left on the keratinic fibers for a period of 5 to 50 minutes at a temperature of 20 to 45° C. The keratinic fibers are rinsed, and optionally dried. Next, a composition including at least one oxidation dye precursor and at least one oxidizing agent is applied to the keratinic fibers and the keratinic fibers are deformed. That composition is allowed to act for 10 to 35 minutes. An aqueous composition including at least one oxidizing agent, is applied to the keratinic fibers for 30 seconds to 15 minutes. The keratinic fibers are rinsed out, along with removal of the deformation aids.

  一种在单一过程中对角蛋白进行永久塑形和改色的方法包括以下步骤。首先，将包括至少一种角质还原化合物和至少一种碱化剂的水性组合物涂在角质纤维上，并在 20 至 45 摄氏度的温度下在角质纤维上停留 5 至 50 分钟。然后，将包括至少一种氧化染料前体和至少一种氧化剂的组合物涂在角质纤维上，并使角质纤维变形。让该组合物作用 10 至 35 分钟。将包括至少一种氧化剂的水性组合物涂抹在角质纤维上 30 秒至 15 分钟。冲洗角质纤维，同时去除变形辅助剂。