4-Piperidin-1-yl-1-(1,2,3,4-tetrahydronaphthalen-1-yl)piperidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 4-Piperidin-1-yl-1-(1,2,3,4-tetrahydronaphthalen-1-yl)piperidine
• 化学式: C₂₀H₃₀N₂
• 分子量: 298.5
• InChiKey: VDFRPLWJIDIXGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 4-AMINOPIPERIDINE DERIVATIVES OF TETRAHYDRONAPHTHALENE, CHROMANS AND THIOCHROMANS
  申请人：AstraZeneca UK Limited

  公开号：EP1204641A1

  公开（公告）日：2002-05-15
• [EN] 4-AMINOPIPERIDINE DERIVATIVES OF TETRAHYDRONAPHTHALENE, CHROMANS AND THIOCHROMANS<br/>[FR] DERIVES 4-AMINOPIPERIDINE DE TETRAHYDRONAPHTALENE, CHROMANS ET THIOCHROMANS
  申请人：ASTRAZENECA UK LTD

  公开号：WO2000078718A1

  公开（公告）日：2000-12-28

  1,2,3,4-tetrahydronaphthalenes, chromans and thiochromans, of formula (I), wherein r, s and X are as defined in the specifications, R?1, R2, R3 and R4¿ are various substituents, also as defined in the specification, pharmaceutical compositions containing them and uses of them for the therapeutic treatment of neurological disorders.