[(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S)-3-[3-[4-(3-aminopropylamino)butylamino]propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S)-3-[3-[4-(3-aminopropylamino)butylamino]propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate
• 化学式: C₃₇H₇₂N₄O₅S
• 分子量: 685.1
• InChiKey: WUJVPODXELZABP-ULRMNHNTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  47
• 可旋转键数：
  20
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  154
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• METHODS AND COMPOSITIONS FOR STIMULATION OF THE INTESTINAL ENTEROENDOCRINE SYSTEM FOR TREATING DISEASES OR CONDITIONS RELATED TO THE SAME
  申请人：Zasloff Michael

  公开号：US20150368290A1

  公开（公告）日：2015-12-24

  This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias , or derivatives thereof, to a subject in need.
• US8101583B2
  申请人：——

  公开号：US8101583B2

  公开（公告）日：2012-01-24