(11R,13S,17R)-11-(4-acetylphenyl)-13-methyl-3'-methylidenespiro[1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-17,2'-oxolane]-3-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (11R,13S,17R)-11-(4-acetylphenyl)-13-methyl-3'-methylidenespiro[1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-17,2'-oxolane]-3-one
• 化学式: C₃₀H₃₄O₃
• 分子量: 442.6
• InChiKey: YNWTZVKFWBTFFE-ZVHIGBTLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  33
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• PROGESTERONE ANTAGONISTS
  申请人：Nickisch Klaus

  公开号：US20130029953A1

  公开（公告）日：2013-01-31

  Described herein are compounds which either act as pure antiprogestins or as antiprogestins with partial agonistic activity and methods of treating cancer using such compounds.

  本文描述了一些化合物，它们可以作为纯抗孕激素或具有部分激动活性的抗孕激素，并且使用这些化合物的方法治疗癌症。
• SKELETAL MUSCLE HYPERTROPHY INDUCERS
  申请人：CYTOO

  公开号：US20200054649A1

  公开（公告）日：2020-02-20

  The present invention relates to skeletal muscle hypertrophy inducers as well as their uses to promote skeletal muscle regeneration, to prevent skeletal muscle atrophy, or in the treatment or prevention of a disease or injury resulting in loss of skeletal muscle tissue and/or muscle weakness. It further relates to the non-therapeutic use of such compounds to increase muscle mass, muscle strength and/or muscle performance in a subject.
• US8673968B2
  申请人：——

  公开号：US8673968B2

  公开（公告）日：2014-03-18