(7R,8S)-2,3-dimethyl-7-morpholin-4-yl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridin-8-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: (7R,8S)-2,3-dimethyl-7-morpholin-4-yl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridin-8-ol
• 化学式: C₁₆H₂₂N₄O₂
• 分子量: 302.37
• InChiKey: NCSPUPQIBOHNIH-DZGCQCFKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  62
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Amino-substituted imidazopyridines for the treatment of gastrointestial diseases
  申请人：——

  公开号：US20040235882A1

  公开（公告）日：2004-11-25

  Compounds of the formula (I), in which the substituents and symbols are as defined in the description are suitable for preventing and treating gastrointestinal disorders. 1

  式(I)的化合物，其中所定义的取代基和符号适用于预防和治疗胃肠道疾病。
• Combinations and use of selected pharmaceutically active compounds
  申请人：Buhr Wilm

  公开号：US20060154954A1

  公开（公告）日：2006-07-13

  The present invention relates to new combinations and new uses of certain selected tricyclic imidazo [ 1,2 -a]pyridine compounds in the prevention or treatment of medicament caused gastrointestinal diseases.

  本发明涉及某些精选三环咪唑[1,2]的新组合和新用途。 1,2 -a]吡啶化合物在预防或治疗药物引起的胃肠道疾病方面的新组合和新用途。
• PHARMACEUTICAL COMBINATIONS OF A PROTON PUMP INHIBITOR AND A COMPOUND WHICH MODIFIES GASTROINTESTINAL MOTILITY
  申请人：ALTANA Pharma AG

  公开号：EP1644043A1

  公开（公告）日：2006-04-12
• Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
  申请人：Buhr Wilm

  公开号：US20060241134A1

  公开（公告）日：2006-10-26

  The invention relates to the combination of certain active compounds from the acid pump antagonist class and compounds which modify gastrointestinal motility.
• [EN] PHARMACEUTICAL COMBINATIONS OF A PROTON PUMP INHIBITOR AND A COMPOUND WHICH MODIFIES GASTROINTESTINAL MOTILITY<br/>[FR] COMBINAISONS PHARMACEUTIQUES D'UN INHIBITEUR DE LA POMPE A PROTONS ET D'UN COMPOSE MODIFIANT LA MOTILITE GASTRO-INTESTINALE
  申请人：ALTANA PHARMA AG

  公开号：WO2004105795A1

  公开（公告）日：2004-12-09

  The invention relates to the combination of certain active compounds from the acid pump antagonist class and compounds, which modify gastrointestinal motility.