6-hydroxy-2-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-naphthalen-1-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 6-hydroxy-2-(naphthalen-2-ylmethyl)-3,4-dihydro-2H-naphthalen-1-one
• 化学式: C₂₁H₁₈O₂
• 分子量: 302.4
• InChiKey: WSHMOGJTTNVRPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] BENZYL TETRALINS, FORMULATIONS AND USES THEREOF<br/>[FR] BENZYL-TETRALINES, FORMULATIONS ET UTILISATIONS ASSOCIEES
  申请人：UNIV CARDIFF

  公开号：WO2001042181A1

  公开（公告）日：2001-06-14

  A benzyl tetralin represented by general formula (I), or a pharmaceutically acceptable salt or prodrug thereof where X is selected from the group consisting of halogen, C1-6 alkyl optionally substituted by at least one halogen, a fused bicyclic hydrophobic ring system and phenyl optionally substituted by at least one halogen; Y is selected from the group consisting of hydrogen and halogen; or X and Y together form the residue of a carbocyclic ring.