(3R)-1-[2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol;hydrochloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (3R)-1-[2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol;hydrochloride
• 化学式: C20H32ClNO4
• 分子量: 385.9
• InChiKey: JMHYCBFEEFHTMK-DSKXPBBKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.06
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  51.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] USES OF ION CHANNEL MODULATING COMPOUNDS<br/>[FR] UTILISATIONS DE COMPOSES MODULANT LES CANAUX IONIQUES
  申请人：CARDIOME PHARMA CORP

  公开号：WO2004098525A2

  公开（公告）日：2004-11-18

  Methods, formulations, dosing regimes, and routes of administration for the treatment or prevention of arrhythmias, including the treatment or prevention of atrial fibrillation. In these methods, the disease or condition is treated or prevented by administering one or more ion channel modulating compounds to a subject, where the ion channel modulating compound or compounds produce specific plasma levels in the subject. The ion channel modulating compounds may be cycloalkylamine ether compounds, particularly cyclohexylamine ether compounds.